P-cadherin expression in breast cancer: a review.

P-cadherin expression in breast cancer: a review. Research Abstract Details 

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P-cadherin expression in breast cancer: a review. Abstract Text:

Joana Paredes, Correia,Ana Sofia Ribeiro, Albergaria,Fernanda Milanezi,Fernando C Schmitt,Joana Paredes, Correia,Ana Sofia Ribeiro, Albergaria,Fernanda Milanezi,Fernando C Schmitt,Joana Paredes, Correia,Ana Sofia Ribeiro, Albergaria,Fernanda Milanezi,Fernando C Schmitt,

ABSTRACT : P-cadherin is frequently over-expressed in high-grade invasive breast carcinomas and has been reported to be an enhancer of migration and invasion of breast cancer cells, being correlated with tumour aggressiveness. In addition, expression of P-cadherin is well established as an indicator of poor prognosis in human breast cancer, which has stimulated our interest in studying its role in this setting. This review describes the most important findings on P-cadherin expression and function in normal mammary tissue and breast cancer cells, emphasizing that further research is required to elucidate the role played by this protein in human mammary tumours.

P-cadherin expression in breast cancer: a review. Publishing Authors By Initials

J Paredes,AL Correia,AS Ribeiro,A Albergaria,F Milanezi,FC Schmitt,J Paredes,AL Correia,AS Ribeiro,A Albergaria,F Milanezi,FC Schmitt,J Paredes,AL Correia,AS Ribeiro,A Albergaria,F Milanezi,FC Schmitt,

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P-cadherin expression in breast cancer: a review. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Breast cancer research : BCR

VOLUME: 9

Page Numbers: 214

Journal Abbreviation: Breast Cancer Res.

ISSN: 1465-542X

DAY: 16

MONTH: 01

YEAR: 2007

P-cadherin expression in breast cancer: a review. Information

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LANGUAGE: eng

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AFFILIATION: Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. jparedes@ipatimup.pt.

Country: England

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MEDLINETA: Breast Cancer Res

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