[Ovarian secretion of estrogens in Stein-Leventhal syndrome]

[Ovarian secretion of estrogens in Stein-Leventhal syndrome] Research Abstract Details 

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[Ovarian secretion of estrogens in Stein-Leventhal syndrome] Abstract Text:

I Csaba,G Bücs,I Szabó,P Nagy,A Major,

Over an 8-year period, 75 Stein-Leventhal patients underwent curettage; 47 of them also had a determination of estrogen secretion. Levels were normal for 49, increased for 16 and were below normal for 10. Endometrial proliferation was found in 33 patients with a total estrogen secretion of 13 mcg/24 hours. Of these 33, 18 also displayed hirsutism. 23% or 17 of the 75 patients showed endometrial hyperplasia but their estrogen secretion was within normal values with the exception of 3 women. Hirsutism was seen in 7 of the patients. An atrophic endometrium was seen in 5 patients, one of whom had a moderate hirsutism; their estrogen levels fluctuated from 10 to 16.5 mcg/24 hours. Hirsutism was the dominant clinical sign in 20 patients with an inactive endometrium and an estrogen level of 10 mcg/24 hours. 17-Ketosteroids and their fractions were independent of the hirsutism and within normal levels. In the absence of ovulation, pregnandiol excretion was low. 48% of the patients with hirsutism (36 cases) did not have estrogen secretion values outside the normal. The results confirm that estrogen secretion in the polycystic ovary does not decrease and that the frequent endometrial hyperplasia is even a direct consequence of persistent estrogen action. That these patients also preserved their female phenotype supports the fact of estrogen sufficiency in the case of the polycystic ovary.

[Ovarian secretion of estrogens in Stein-Leventhal syndrome] Publishing Authors By Initials

I Csaba,G Bücs,I Szabó,P Nagy,A Major,

For similar diagnosis: diagnostic techniques and procedures: diagnostic techniques, obstetrical and gynecological: vaginal smears research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic techniques, obstetrical and gynecological: vaginal smears research

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[Ovarian secretion of estrogens in Stein-Leventhal syndrome] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zentralblatt für Gynäkologie

VOLUME: 96

Page Numbers: 570-5

Journal Abbreviation: Zentralbl Gynakol

ISSN: 0044-4197

DAY: 3

MONTH: May

YEAR: 1974

[Ovarian secretion of estrogens in Stein-Leventhal syndrome] Information

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LANGUAGE: ger

NlmUniqueID: 21820100

[Ovarian secretion of estrogens in Stein-Leventhal syndrome] Keywords Mesh Terms:

KEYWORDS: Vaginal Smears

MESH TERMS: physiopathology

Chemical & Substance for Abstract: [Ovarian secretion of estrogens in Stein-Leventhal syndrome] Information

Substance Name: Estrogens

Registry Number: 0

Grant and Affiliation Information for [Ovarian secretion of estrogens in Stein-Leventhal syndrome]

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Country: GERMANY, EAST

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MEDLINETA: Zentralbl Gynakol

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