Outcome of patients with hormone-refractory prostate cancer: prognostic significance of prostate-specific antigen-doubling time and nadir prostate-specific antigen.

Outcome of patients with hormone-refractory prostate cancer: prognostic significance of prostate-specific antigen-doubling time and nadir prostate-specific antigen. Research Abstract Details 

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Outcome of patients with hormone-refractory prostate cancer: prognostic significance of prostate-specific antigen-doubling time and nadir prostate-specific antigen. Abstract Text:

Susumu Tomioka,Masashi Shimbo,Yoshiyasu Amiya,Hiroomi Nakatsu,Shino Murakami,Jun Shimazaki,

OBJECTIVE: Most patients with advanced prostate cancer after prostate-specific antigen (PSA) relapse following maximum androgen blockade rapidly progress to death. The present study was aimed to predict the survival of these serious patients after PSA relapse. METHODS: Sixty-eight patients with M1b and 20 patients with T3b, who relapsed and died of cancer within a short period, were studied. PSA-doubling time (PSA-DT) at PSA relapse influenced the outcome after PSA relapse [hazard ratio (CI): 2.000 (1.283-3.226)]; thus, on the basis of the median values of PSA-DT (>2 months) and additionally nadir PSA in previous treatment (2 months and nadir PSA of

Outcome of patients with hormone-refractory prostate cancer: prognostic significance of prostate-specific antigen-doubling time and nadir prostate-specific antigen. Publishing Authors By Initials

S Tomioka,M Shimbo,Y Amiya,H Nakatsu,S Murakami,J Shimazaki,

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Outcome of patients with hormone-refractory prostate cancer: prognostic significance of prostate-specific antigen-doubling time and nadir prostate-specific antigen. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Japanese journal of clinical oncology

VOLUME: 38

Page Numbers: 36-42

Journal Abbreviation: Jpn. J. Clin. Oncol.

ISSN: 1465-3621

DAY: 8

MONTH: Jan

YEAR: 2008

Outcome of patients with hormone-refractory prostate cancer: prognostic significance of prostate-specific antigen-doubling time and nadir prostate-specific antigen. Information

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LANGUAGE: eng

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AFFILIATION: Department of Urology, Graduate School of Medicine, Chiba University, Inohana, Chuo-ku, Chiba-shi 260-8670, Japan.

Country: Japan

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MEDLINETA: Jpn J Clin Oncol

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