Outcome after endografting in small and large abdominal aortic aneurysms: a metanalysis.

Outcome after endografting in small and large abdominal aortic aneurysms: a metanalysis. Research Abstract Details 

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Outcome after endografting in small and large abdominal aortic aneurysms: a metanalysis. Abstract Text:

P De Rango,P Cao,G Parlani,F Verzini,D Brambilla,P De Rango,P Cao,G Parlani,F Verzini,D Brambilla,P De Rango,P Cao,G Parlani,F Verzini,D Brambilla,

AIM: To compare the results of endovascular repair (EVAR) in large and small (diameter < 5.5cm) abdominal aortic aneurysms (AAA). METHODS: A systematic review was performed to identify studies comparing the outcomes after EVAR of large and small aneurysms. Outcomes considered were: risk of death (perioperative, all cause, aneurysm-related), ruptures, and complications (conversion, reintervention). Weighted pooled estimates of outcomes in patients with small versus large aneurysms were calculated. The inverse variance method was used (random-effect model). Subgroup analyses by a follow-up longer or shorter than 24 months were performed. RESULTS: Five studies, with published and unpublished data, totallying 7,735 patients, were included. Overall, the weighted pooled estimates were: OR 0.68; 95% CI 0.51-0.90 for operative mortality, OR 0.77; 95% CI 0.69 to 0.86 for all cause mortality, OR 0.58; 95% CI 0.40 to 0.87 for aneurysm-related mortality and OR 0.61; 95% CI 0.47 to 0.79 for rupture in favour of small AAA group. Pooled estimates were not influenced by follow-up length. Conversion and reintervention rates were not significantly lower for small AAA. CONCLUSIONS: EVAR in small versus large AAA might be associated with lower operative mortality, aneurysm-related mortality and aneurysm rupture. Better evidence is needed to support these suggestions.

Outcome after endografting in small and large abdominal aortic aneurysms: a metanalysis. Publishing Authors By Initials

P De Rango,P Cao,G Parlani,F Verzini,D Brambilla,P De Rango,P Cao,G Parlani,F Verzini,D Brambilla,P De Rango,P Cao,G Parlani,F Verzini,D Brambilla,

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Outcome after endografting in small and large abdominal aortic aneurysms: a metanalysis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European journal of vascular and endovascular surg

VOLUME: 35

Page Numbers: 162-72

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ISSN: 1532-2165

DAY: 1

MONTH: Feb

YEAR: 2008

Outcome after endografting in small and large abdominal aortic aneurysms: a metanalysis. Information

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LANGUAGE: eng

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AFFILIATION: Division of Vascular and Endovascular Surgery, University of Perugia, Ospedale S. Maria della Misericordia, Perugia, Italy.

Country: England

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MEDLINETA: Eur J Vasc Endovasc Surg

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