Otopathologic correlates of the continuum of otitis media.

Otopathologic correlates of the continuum of otitis media. Research Abstract Details 

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Otopathologic correlates of the continuum of otitis media. Abstract Text:

M M Paparella,P A Schachern,T H Yoon,M M Abdelhammid,R Sahni,S S da Costa,

It has been our hypothesis that different types of middle ear effusions and the clinical manifestations with which they are associated represent the typical inflammatory response. Employing an animal model under controlled conditions, we present statistical evidence that change in the mucosa of the middle ear in otitis media can occur along a continuum, with early forms regressing to more chronic stages of the disease. We also demonstrate an increase in the thickness and a decrease in the permeability of the round window membrane in a longitudinal study of otitis media in the same animal model. Histopathologic changes in human temporal bones with otitis media with effusion or chronic otitis media are similar to the changes in the animal models. These results support a concept that all categories of otitis media (serous, purulent, mucoid, and chronic) represent different stages in a continuum of events.

Otopathologic correlates of the continuum of otitis media. Publishing Authors By Initials

MM Paparella,PA Schachern,TH Yoon,MM Abdelhammid,R Sahni,SS da Costa,

For similar musculoskeletal system: muscles: muscle, skeletal: tensor tympani research abstracts see: musculoskeletal system: muscles: muscle, skeletal: tensor tympani research

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Otopathologic correlates of the continuum of otitis media. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: The Annals of otology, rhinology & laryngology. Su

VOLUME: 148

Page Numbers: 17-22

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ISSN: 0096-8056

DAY: 21

MONTH: Jun

YEAR: 1990

Otopathologic correlates of the continuum of otitis media. Information

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LANGUAGE: eng

NlmUniqueID: 1256156

Otopathologic correlates of the continuum of otitis media. Keywords Mesh Terms:

KEYWORDS: Tensor Tympani

MESH TERMS: pathology

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Grant and Affiliation Information for Otopathologic correlates of the continuum of otitis media.

AFFILIATION: University of Minnesota Otitis Media Research Center, Minneapolis.

Country: UNITED STATES

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MEDLINETA: Ann Otol Rhinol Laryngol Suppl

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