Osteosarcoma: histological evaluation and grading.

Osteosarcoma: histological evaluation and grading. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Osteosarcoma: histological evaluation and grading. Abstract Text:

P Meister,E Konrad,G Lob,G Janka,W Keyl,H Stürz,

With 60 cases of osteosarcomas a histological evaluation from + to +++ carried out for mitoses, osteoid formation, presence of multinucleated giant cells, and tumor necrosis. A subclassification in osteoblastic, chondroblastic, and fibroblastic type of osteosarcoma (according to Dahlin) and a histological grading from + to +++ based on degree of cellular atypism was also done. In our material no relations between these three types of osteosarcoma and chance for survival became evident. There was, however, a significant correlation between grade of atypism and rate of mitoses. Grading of oestosarcomas from + to +++ showed that cases with grade III osteosarcoma remained only seldomly without metastases during the course of the disease. Grade I osteosarcomas and also grade II tumors showed a higher number of patients with 2-year survival. However, neither correlation between tumor grade and incidence of metastases, nor with chances for survival were statistically significant. Nevertheless, characterization of osteosarcomas, by a histological grading from + to +++ based on cellular atypism and mitotic count is advisable, in addition to the TNM stages. This histological grading appeared to be more practicable than subclassifications of osteosarcoma by type which had been tested by us in a previous study (Konrad et al., in press).

Osteosarcoma: histological evaluation and grading. Publishing Authors By Initials

P Meister,E Konrad,G Lob,G Janka,W Keyl,H Stürz,

For similar diagnosis: prognosis research abstracts see: diagnosis: prognosis research

PUBMED ID PMID:

MEDLINE DATE:

Osteosarcoma: histological evaluation and grading. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archives of orthopaedic and traumatic surgery. Arc

VOLUME: 94

Page Numbers: 91-8

Journal Abbreviation:

ISSN: 0344-8444

DAY: 31

MONTH: Jul

YEAR: 1979

Osteosarcoma: histological evaluation and grading. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7803037

Osteosarcoma: histological evaluation and grading. Keywords Mesh Terms:

KEYWORDS: Prognosis

MESH TERMS: pathology

Chemical & Substance for Abstract: Osteosarcoma: histological evaluation and grading. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Osteosarcoma: histological evaluation and grading.

AFFILIATION:

Country: GERMANY, WEST

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Arch Orthop Trauma Surg

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Osteosarcoma: histological evaluation and grading Related Publications

• Osteosarcoma: histological evaluation and grading.