Origin of renal proximal tubular injuries by Fe(III)-nta chelate.

Origin of renal proximal tubular injuries by Fe(III)-nta chelate. Research Abstract Details 

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Origin of renal proximal tubular injuries by Fe(III)-nta chelate. Abstract Text:

Yuzo Nishida,Yuuta Ito,Takahiro Satoh,Yuzo Nishida,Yuuta Ito,Takahiro Satoh,

Interaction between apo-transferrin and several iron(III) chelates has been investigated in terms of the capillary electrophoresis method. Based on the results, it has been clarified that (i) a binuclear iron(III) unit with an oxo-bridge is necessary for the facile transfer of an iron atom from the iron(III) chelate to apo-transferrin, and (ii) the renal proximal tubular injuries by Fe(III)-nitrilotriacetate (Fe-nta) should be due to the unique binuclear structure of this complex, which gives a peroxide adduct of the binuclear Fe-nta in the presence of glutathione cycle and oxygen.

Origin of renal proximal tubular injuries by Fe(III)-nta chelate. Publishing Authors By Initials

Y Nishida,Y Ito,T Satoh,Y Nishida,Y Ito,T Satoh,

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Origin of renal proximal tubular injuries by Fe(III)-nta chelate. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zeitschrift für Naturforschung. C, Journal of bios

VOLUME: 62

Page Numbers: 608-12

Journal Abbreviation: Z. Naturforsch., C, J. Biosci.

ISSN: 0341-0382

DAY: 4

MONTH: 10

YEAR: 2007

Origin of renal proximal tubular injuries by Fe(III)-nta chelate. Information

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LANGUAGE: eng

NlmUniqueID: 8912155

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AFFILIATION: Department of Chemistry, Faculty of Science, Yamagata University, Yamagata 990-8560, Japan. yuzo@sci.kj.yamagata-u.ac.jp

Country: Germany

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MEDLINETA: Z Naturforsch [C]

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