[Organic lesions after application of hashish in rats and rabbits (author's transl)]

[Organic lesions after application of hashish in rats and rabbits (author's transl)] Research Abstract Details 

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[Organic lesions after application of hashish in rats and rabbits (author's transl)] Abstract Text:

H Janzen,B Ludwig,E Lycko,D Gerlach,

Toxic lesions were found in liver, kidney and brain of rats and rabbits after oral application of hashish for 7 or 30 days. The brain tissue showed hyperemia and edema. The cerebral cortex, brain stem and cerebellum contained ganglion cells with eccentric nuclei and an icreased number of nucleoli. Different stages of cell lesions could be distinguished by nuclear vacuoles, pyknosis and karyolysis. The cytoplasma was loosened and showed numerous vacuoles. In the kidney we found, besides interstitial hemorrhage, cloudy swelling of the proximal tubules with vacuolous degeneration and nuclear pyknosis and karyolysis in all stages. The glomeruli were often enlarged with thickening of Bowman's capsule and surrounding cellular infiltration with cell fragments. The liver cells showed irregularities of nuclei and vacuolated nuclei, plasma vacuoles and cell necrosis. Infiltrations of round cells at the portal-biliary areas were usually combined with an activation of the Kupffer cells and intracellular bile stasis.

[Organic lesions after application of hashish in rats and rabbits (author's transl)] Publishing Authors By Initials

H Janzen,B Ludwig,E Lycko,D Gerlach,

For similar animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats research abstracts see: animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats research

PUBMED ID PMID:

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[Organic lesions after application of hashish in rats and rabbits (author's transl)] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zeitschrift für Rechtsmedizin. Journal of legal me

VOLUME: 80

Page Numbers: 305-9

Journal Abbreviation: Z. Rechtsmed.

ISSN: 0044-3433

DAY: 31

MONTH: Jan

YEAR: 1978

[Organic lesions after application of hashish in rats and rabbits (author's transl)] Information

Number of References:

LANGUAGE: ger

NlmUniqueID: 247437

[Organic lesions after application of hashish in rats and rabbits (author's transl)] Keywords Mesh Terms:

KEYWORDS: Rats

MESH TERMS: metabolism

Chemical & Substance for Abstract: [Organic lesions after application of hashish in rats and rabbits (author's transl)] Information

Substance Name: Adenosine Triphosphatases

Registry Number: EC 3.6.1.-

Grant and Affiliation Information for [Organic lesions after application of hashish in rats and rabbits (author's transl)]

AFFILIATION:

Country: GERMANY, WEST

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MEDLINETA: Z Rechtsmed

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