Oral contraceptive use and risk of breast carcinoma in situ (United States).

Oral contraceptive use and risk of breast carcinoma in situ (United States). Research Abstract Details 

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Oral contraceptive use and risk of breast carcinoma in situ (United States). Abstract Text:

Jasmeet K Gill,Michael F Press,Alpa V Patel,Leslie Bernstein,

OBJECTIVE: Our study assesses the impact of oral contraceptive use on breast carcinoma in-situ (BCIS) risk. METHODS: We conducted a population based case-control study of incident BCIS among black and white women ages 35-64 years residing in Los Angeles County. Case patients (n = 567) were newly diagnosed with BCIS and control participants (n = 614) were identified by random digit dialing between 1 March 1995 and 31 May 1998. All subjects were required to have had a mammogram in the 2 years before case diagnosis or control recruitment. Data were collected during in-person interviews. Multivariable logistic regression analyses provide estimates of odds ratios (ORs) and 95% confidence intervals (95% CIs). RESULTS: Oral contraceptive use was not associated with risk of BCIS (OR = 1.04, 95% CI (0.76-1.42)). Risk did not increase with longer periods of use. No associations with BCIS risk were observed for oral contraceptive use before first term pregnancy, age at first oral contraceptive use, or for time since last use. Risk was not modified by estrogen dose, age, race, or parity. CONCLUSIONS: Our results are consistent with recent results on invasive breast cancer reported for the Women's Contraceptive and Reproductive Experiences Study and show no association between oral contraceptive use and risk of BCIS.

Oral contraceptive use and risk of breast carcinoma in situ (United States). Publishing Authors By Initials

JK Gill,MF Press,AV Patel,L Bernstein,

For similar investigative techniques: epidemiologic methods: data collection: registries: seer program research abstracts see: investigative techniques: epidemiologic methods: data collection: registries: seer program research

PUBMED ID PMID:

MEDLINE DATE:

Oral contraceptive use and risk of breast carcinoma in situ (United States). Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Cancer causes & control : CCC

VOLUME: 17

Page Numbers: 1155-62

Journal Abbreviation: Cancer Causes Control

ISSN: 0957-5243

DAY: 3

MONTH: Nov

YEAR: 2006

Oral contraceptive use and risk of breast carcinoma in situ (United States). Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9100846

Oral contraceptive use and risk of breast carcinoma in situ (United States). Keywords Mesh Terms:

KEYWORDS: SEER Program

MESH TERMS: epidemiology

Chemical & Substance for Abstract: Oral contraceptive use and risk of breast carcinoma in situ (United States). Information

Substance Name: Contraceptives, Oral

Registry Number: 0

Grant and Affiliation Information for Oral contraceptive use and risk of breast carcinoma in situ (United States).

AFFILIATION: Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI, USA.

Country: Netherlands

AGENCY: United States NCI

GRANT: N01-PC-35139

ACRONYM: PC

MEDLINETA: Cancer Causes Control

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