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Oral cobalamin remains medicine's best kept secret.

Oral cobalamin remains medicine's best kept secret. Research Abstract Details 

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  • Oral cobalamin remains medicine's best kept secret. Abstract Text:

    ian d grahamIan D Graham,nathalie jetteNathalie Jette,jacqueline tetroeJacqueline Tetroe,nicole robinsonNicole Robinson,sarah milneSarah Milne,susan l mitchellSusan L Mitchell,

    A cross-sectional survey was conducted in order to describe the use of oral cobalamin among geriatricians, hematologists, and general practitioners, and to explore factors related to its use. The study population consisted of all geriatricians (n = 138) and hematologists (n = 317) listed in the Canadian Medical Directory plus a random sample of 307 general practitioners. The overall response rate was 40%. Intramuscular and oral cobalamin was prescribed by 76 and 32% of the respondents, respectively. Twenty seven percent reported using both oral and intramuscular cobalamin and 6% reported using only oral cobalamin. Only 25% of respondents indicated they were aware of a RCT demonstrating the efficacy of oral cobalamin prior to reading a synopsis of the study in the survey. After multivariate adjustment, only the belief that oral cobalamin was effective and certainty about who carried oral preparations remained independently associated with oral cobalamin use. Oral cobalamin has been shown to be an efficacious, cost efficient and safe method of treating cobalamin deficiency. Nonetheless, it is not used by the majority of physicians treating this condition. Strategies to promote the use of oral cobalamin should be directed at educating physicians of its efficacy and providing them with prescribing information on where it can be purchased.

    Oral cobalamin remains medicine's best kept secret. Publishing Authors By Initials

    id grahamID Graham,n jetteN Jette,j tetroeJ Tetroe,n robinsonN Robinson,s milneS Milne,sl mitchellSL Mitchell,

    For similar chemical actions and uses: pharmacologic actions: physiological effects of drugs: growth substances: micronutrients: vitamins: vitamin b complex research abstracts see: chemical actions and uses: pharmacologic actions: physiological effects of drugs: growth substances: micronutrients: vitamins: vitamin b complex research

    PUBMED ID PMID:

    MEDLINE DATE:

    Oral cobalamin remains medicine's best kept secret. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Archives of gerontology and geriatrics

    VOLUME: 44

    Page Numbers: 49-59

    Journal Abbreviation:

    ISSN: 0167-4943

    DAY: 2

    MONTH: 05

    YEAR: 2006

    Oral cobalamin remains medicine's best kept secret. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8214379

    Oral cobalamin remains medicine's best kept secret. Keywords Mesh Terms:

    KEYWORDS: Vitamin B Complex

    MESH TERMS: administration & dosage

    Chemical & Substance for Abstract: Oral cobalamin remains medicine's best kept secret. Information

    Substance Name: Vitamin B 12

    Registry Number: 68-19-9

    Grant and Affiliation Information for Oral cobalamin remains medicine's best kept secret.

    AFFILIATION: Clinical Epidemiology Program, Ottawa Health Research Institute, Room 2-008, Administrative Services Building, 1053 Carling Ave., Ottawa, Ont., Canada K1Y 4E9. igraham@ohri.ca

    Country: Netherlands

    Netherlands Research PublicationNetherlands Research Publication

    AGENCY: United States NIA

    GRANT: R01 AG024091

    ACRONYM: AG

    MEDLINETA: Arch Gerontol Geriatr

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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