Oral calcium supplementation associated with decreased likelihood of nephrolithiasis prior to surgery for hyperparathyroidism.

Oral calcium supplementation associated with decreased likelihood of nephrolithiasis prior to surgery for hyperparathyroidism. Research Abstract Details 

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Oral calcium supplementation associated with decreased likelihood of nephrolithiasis prior to surgery for hyperparathyroidism. Abstract Text:

Matthew R Cooperberg,Quan-Yang Duh,G Bennett Stackhouse,Marshall L Stoller,Matthew R Cooperberg,Quan-Yang Duh,G Bennett Stackhouse,Marshall L Stoller,Matthew R Cooperberg,Quan-Yang Duh,G Bennett Stackhouse,Marshall L Stoller,

We aimed to assess the impact of oral calcium supplementation (OCS) on the prevalence of nephrolithiasis among a cohort of patients undergoing surgery for primary hyperparathyroidism (PHPT). There were 339 patients undergoing surgery for PHPT with detailed past medical history data that were analyzed. 73 patients (22%) had a history of nephrolithiasis prior to parathyroid surgery. Nephrolithiasis was more common among men than women (40% vs 15%, P < 0.001), despite the predominance of women (73% of patients) with hyperparathyroidism. 83 patients (25%) used OCS. OCS was associated with a lower prevalence of nephrolithiasis (9.6% vs 25.4% without OCS, P = 0.002). This protective effect included both men and women (rates of nephrolithiasis with and without supplements: men 19% vs 46%, P = 0.027; women 7% vs 17%, P = 0.04). The mechanism for the apparent protective effect of OCS on rates of nephrolithiasis is unclear, and further research is required to elucidate the variable penetrance of nephrolithiasis among PHPT patients.

Oral calcium supplementation associated with decreased likelihood of nephrolithiasis prior to surgery for hyperparathyroidism. Publishing Authors By Initials

MR Cooperberg,QY Duh,GB Stackhouse,ML Stoller,MR Cooperberg,QY Duh,GB Stackhouse,ML Stoller,MR Cooperberg,QY Duh,GB Stackhouse,ML Stoller,

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Oral calcium supplementation associated with decreased likelihood of nephrolithiasis prior to surgery for hyperparathyroidism. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: International journal of urology : official journa

VOLUME: 14

Page Numbers: 1113-5

Journal Abbreviation: Int. J. Urol.

ISSN: 0919-8172

DAY: 26

MONTH: Dec

YEAR: 2007

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LANGUAGE: eng

NlmUniqueID: 9440237

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Grant and Affiliation Information for Oral calcium supplementation associated with decreased likelihood of nephrolithiasis prior to surgery for hyperparathyroidism.

AFFILIATION: Department of Urology, University of California, San Francsico, San Francisco, California, USA.

Country: Australia

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MEDLINETA: Int J Urol

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