Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry.

Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry. Abstract Text:

J J Luci,H M Whitney,J C Gore,

Polymer gel dosimetry aims to provide three-dimensional images of radiation therapy dose distributions in irradiated aqueous gels. The first gels required manufacture in an oxygen-free environment, but later the MAGIC formulation was introduced, which could be made in normal atmospheric conditions. Here we report our studies of the effects of variations in the composition of the MAGIC gel performed in order to optimize its performance over the useful dose range of 0 to 20 Gy. A new formulation (termed 'MAGIC-2') is comprised of 87% water, 4% methacrylic acid, 9% gelatin, 17.38 x 10(-6) M Cu(2+) and a molar ratio of ascorbic acid to [Cu(2+)] of 1000:1. MAGIC-2 has a dose-response slope-to-intercept ratio that is 78% greater than the original formulation and other more favorable properties.

Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry. Publishing Authors By Initials

JJ Luci,HM Whitney,JC Gore,

For similar water research abstracts see: water research

PUBMED ID PMID:

MEDLINE DATE:

Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Physics in medicine and biology

VOLUME: 52

Page Numbers: N241-8

Journal Abbreviation:

ISSN: 0031-9155

DAY: 23

MONTH: 04

YEAR: 2007

Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 401220

Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry. Keywords Mesh Terms:

KEYWORDS: Water

MESH TERMS: chemistry

Chemical & Substance for Abstract: Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry. Information

Substance Name: Gelatin

Registry Number: 9000-70-8

Grant and Affiliation Information for Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry.

AFFILIATION: Vanderbilt University Institute of Imaging Science, Nashville, TN 37232-2675, USA.

Country: England

AGENCY: United States NIBIB

GRANT: R01 EB000214

ACRONYM: EB

MEDLINETA: Phys Med Biol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry Related Publications

• A Phase II study of trabectedin single agent in patients with recurrent ovarian cancer previously treated with platinum-based regimens.
• A practical guide to robust detection of GABA in human brain by J-difference spectroscopy at 3 T using a standard volume coil.
• Adverse childhood experiences and mental health in young adults: a longitudinal survey.
• Amphibian emergency medicine.
• An Arabidopsis haplotype map takes root.
• Assessing functional connectivity in the human brain by fMRI.
• Assessing signal enhancement in distant dipolar field-based sequences.
• Calculation of RF Peak Power for 2D Arbitrary Shape Excitation in MRI.
• Comment on "Assessing functional connectivity in the human brain by fMRI".
• Comparison of a reference region model with direct measurement of an AIF in the analysis of DCE-MRI data.
• Detection and isolation of Japanese encephalitis virus from blood clots collected during the acute phase of infection.
• Development of 2dTCA for the detection of irregular, transient bold activity.
• Development of left occipitotemporal systems for skilled reading in children after a phonologically- based intervention.
• Effects of hypoglycemia on human brain activation measured with fMRI.
• Estrogenic environmental endocrine-disrupting chemical effects on reproductive neuroendocrine function and dysfunction across the life cycle.
• Hypoglycemia reduces the blood-oxygenation level dependent signal in primary auditory and visual cortex: a functional magnetic resonance imaging study.
• Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging.
• Integration of quantitative DCE-MRI and ADC mapping to monitor treatment response in human breast cancer: initial results.
• Long-term trends in the use of coronary reperfusion strategies in acute myocardial infarction: a community-wide perspective.
• Molecular imaging of vascular endothelial growth factor receptor 2 expression using targeted contrast-enhanced high-frequency ultrasonography.
• Novel localization of NMDA receptors within neuroendocrine gonadotropin-releasing hormone terminals.
• Numerical study of water diffusion in biological tissues using an improved finite difference method.
• Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry.
• Quantitative magnetization transfer imaging via selective inversion recovery with short repetition times.
• Randomized adjuvant therapy trials in melanoma: surgical and systemic.
• Repeatability of a reference region model for analysis of murine DCE-MRI data at 7T.
• Serum glucose levels and hospital outcomes in patients with acute myocardial infarction without prior diabetes: a community-wide perspective.
• The effects of prenatal PCBs on adult female paced mating reproductive behaviors in rats.
• Tracking the migration of dendritic cells by in vivo optical imaging.
• Why endocrinologists need to take ownership of endocrine disruption.