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Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology.

Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology. Research Abstract Details 

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  • Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology. Abstract Text:

    Angiotensin I-converting enzyme (ACE) inhibitory peptides have been shown to have antihypertensive effects and have been utilized for physiologically functional foods and pharmaceuticals. The ACE inhibitory ability of a hydrolysate is determined by its peptide composition. However, the peptide composition of a hydrolysate depends on proteolytic enzyme and the hydrolysis conditions. In this study, the effect of process conditions on the ACE inhibitory activity of rice dregs hydrolyzed with a trypsin was investigated systematically using response surface methodology. It was shown that the ACE inhibitory activity of rice dregs hydrolysates could be controlled by regulation of five process conditions. Hydrolysis conditions for optimal ACE inhibition were defined using the response surface model of fractional factorial design (FFD), steepest ascent design, and central composite design (CCD).

    Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology. Publishing Authors By Initials

    For similar proteins: protein hydrolysates research abstracts see: proteins: protein hydrolysates research

    PUBMED ID PMID:

    MEDLINE DATE:

    Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Journal of Zhejiang University. Science. B

    VOLUME: 6

    Page Numbers: 508-13

    Journal Abbreviation:

    ISSN: 1673-1581

    DAY: 25

    MONTH: Jun

    YEAR: 2005

    Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 101236535

    Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology. Keywords Mesh Terms:

    KEYWORDS: Protein Hydrolysates

    MESH TERMS: chemistry

    Chemical & Substance for Abstract: Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology. Information

    Substance Name: Peptidyl-Dipeptidase A

    Registry Number: EC 3.4.15.1

    Grant and Affiliation Information for Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology.

    AFFILIATION: Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310029, China. gqhe@zju.edu.cn

    Country: China

    China Research PublicationChina Research Publication

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    GRANT:

    ACRONYM:

    MEDLINETA: J Zhejiang Univ Sci B

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