Optic nerve compression in craniofacial fibrous dysplasia: the role and indications for decompression.

Optic nerve compression in craniofacial fibrous dysplasia: the role and indications for decompression. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Optic nerve compression in craniofacial fibrous dysplasia: the role and indications for decompression. Abstract Text:

Ying-Chien Tan,Chung-Chih Yu,Chen-Nen Chang,Lih Ma,Yu-Ray Chen,Ying-Chien Tan,Chung-Chih Yu,Chen-Nen Chang,Lih Ma,Yu-Ray Chen,Ying-Chien Tan,Chung-Chih Yu,Chen-Nen Chang,Lih Ma,Yu-Ray Chen,

BACKGROUND:: Fibrous dysplasia is a benign bone disorder in which craniofacial bones are involved in approximately one-fifth of cases. Optic nerve compression is one of its most potentially devastating complications. The approach to visual disturbance caused by disease involvement of the optic canal has been varied and controversial. This is especially the case with regard to surgical decompression, particularly prophylactic decompression. METHODS:: The authors performed a retrospective review of fibrous dysplasia patients who showed clinical or radiographic evidence of optic canal involvement over a 27-year period. RESULTS:: Twenty-two optic canals in 18 patients were affected by disease. Of these, 14 optic canals had symptoms (i.e., affected visual acuity or visual field). Twelve therapeutic and six prophylactic optic nerve decompressions were performed in total. At long-term follow-up (of at least 1 year), there was deterioration of vision in one-third of the patients who had undergone prophylactic decompression. Therapeutic decompression seemed to prevent visual deterioration in slightly more than half of the patients, with the majority having improvement in vision. There was visual deterioration in the remaining patients within this group, with most ultimately ending up with blindness. CONCLUSIONS:: Therapeutic optic nerve decompression is advocated in patients with continuous deterioration of vision. Prophylactic decompression, in contrast, is not advised to be performed as a primary surgical procedure but as a procedure secondary to excision of lesion in the anterior skull base during the same operation.

Optic nerve compression in craniofacial fibrous dysplasia: the role and indications for decompression. Publishing Authors By Initials

YC Tan,CC Yu,CN Chang,L Ma,YR Chen,YC Tan,CC Yu,CN Chang,L Ma,YR Chen,YC Tan,CC Yu,CN Chang,L Ma,YR Chen,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Optic nerve compression in craniofacial fibrous dysplasia: the role and indications for decompression. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Plastic and reconstructive surgery

VOLUME: 120

Page Numbers: 1957-62

Journal Abbreviation: Plast. Reconstr. Surg.

ISSN: 1529-4242

DAY: 19

MONTH: Dec

YEAR: 2007

Optic nerve compression in craniofacial fibrous dysplasia: the role and indications for decompression. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 1306050

Optic nerve compression in craniofacial fibrous dysplasia: the role and indications for decompression. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Optic nerve compression in craniofacial fibrous dysplasia: the role and indications for decompression. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Optic nerve compression in craniofacial fibrous dysplasia: the role and indications for decompression.

AFFILIATION: Singapore; and Taipei, Taiwan From the Department of Plastic Surgery, Singapore General Hospital, and the Craniofacial Center and Departments of Neurosurgery and Ophthalmology, Chang Gung Memorial Hospital.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Plast Reconstr Surg

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Optic nerve compression in craniofacial fibrous dysplasia: the role and indications for decompression Related Publications

• A new function of BMP4: dual role for BMP4 in regulation of Sonic hedgehog expression in the mouse tooth germ.
• An experimental study of anti-angiogenesis with recombinant human kringle 5.
• Application of Nd-Yag laser for gingivoplasty during orthodontic treatment.
• Clinical study of alveolar vertical distraction osteogenesis for implant.
• Enzyme-linked immunosorbent assay for the determination of p21-activated kinase activity.
• Hemorheology and expression of neutrophil adhesion molecules CD18 and CD62L in pancreatic microcirculation of Caerulein induced experimental acute pancreatitis.
• Lack of effect of dietary alpha-tocopherol on chemically induced hepatocarcinogenesis in rats.
• Prostaglandin E2 is involved in the increase of cytochrome P-450 2B1 expression by alpha-tocopheryl succinate in primary rat hepatocytes in the presence of phenobarbital.
• Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis.
• Transgenically ectopic expression of Bmp4 to the Msx1 mutant dental mesenchyme restores downstream gene expression but represses Shh and Bmp2 in the enamel knot of wild type tooth germ.
• [A study on apoptosis and activity of SAPK/JNK in adrenocortical cells induced by cadmium chloride]
• [A study on central zone contour of tooth-crown vesticular surface among young people with normal occlusion]
• [Bone-inducing activity of human bone morphogenetic protein-2 102 peptide]
• [Comparative effects of tensiomin and sodium dimercaptosulphonate on the serum sulfydryl and anticopper of the patients with Wilson's disease]
• [Effects of fluoride on the expression of c-fos and c-jun genes and cell proliferation of rat osteoblasts]
• [Establishment of EBV-immortalized lymphoblast cell lines from three Chinese Fanconi anemia patient and their subtyping]
• [Experimental methods for mechanically stimulating the cells in vitro]
• [Focal adhesion kinase]
• [GATA-2 gene expression in leukemia patients and its significance]
• [Genetic polymorphisms of cytochrome P450 1A1 and susceptibility of early-onset Parkinson's disease]
• [Influence of chemotherapy on hematopoietic microenvironment and effect of autologous bone marrow stromal cell infusion on the recovery of hematopoiesis after chemotherapy]
• [Influence of the stratum corneum and dermis of the skin on the percutaneous absorption of fluorouracil delivered through skin patch]
• [Isolation, cultivation and identification of neural stem cell from human embryonic CNS]
• [Melanoma antigen-3 expression in human hepatocellular carcinoma]
• [Novel full-length cDNA cloning from normal adrenal gland and pheochromocytoma and functional prediction]
• [Preparation and application of a new chloromethylstyrene encapsulated silica single anion column]
• [Study on the intestinal microbial colonization resistance in patients with chronic severe hepatitis]
• [Synergetic transactivating functions of HCV core and truncated HBV middle surface protein]
• [Telomerase activity and cellular apoptosis of bladder cancers]
• [The apolipoprotein E gene polymorphism in children with steroid-resistant idiopathic nephrotic syndrome]