Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis.

Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis. Research Abstract Details 

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Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis. Abstract Text:

Marisa I ,Alice Prince,

Pseudomonas aeruginosa is an opportunistic pathogen that significantly contributes to morbidity and mortality in patients with cystic fibrosis. Defective mucociliary clearance associated with the absence of the functional cystic fibrosis transmembrane conductance regulator in airway epithelium plays a critical role in the initial colonization of this pathogen. P. aeruginosa, while initiating a profound inflammatory response, employs multiple mechanisms to evade immune clearance. The capacity to grow in biofilms and the selection of mutants with a mucoid phenotype are major adaptations that allow its persistence in the airways.

Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis. Publishing Authors By Initials

MI ,A Prince,

For similar respiratory system: respiratory mucosa research abstracts see: respiratory system: respiratory mucosa research

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Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis. Journal Published:

PUBLICATION TYPE: Review

Journal: Current opinion in pharmacology

VOLUME: 7

Page Numbers: 244-51

Journal Abbreviation:

ISSN: 1471-4892

DAY: 5

MONTH: 04

YEAR: 2007

Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis. Information

Number of References: 75

LANGUAGE: eng

NlmUniqueID: 100966133

Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis. Keywords Mesh Terms:

KEYWORDS: Respiratory Mucosa

MESH TERMS: microbiology

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Grant and Affiliation Information for Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis.

AFFILIATION: Department of Pediatrics, College of Physicians & Surgeons, Columbia University, New York, NY 10032, USA.

Country: England

AGENCY: United States NHLBI

GRANT: R01HL079395

ACRONYM: HL

MEDLINETA: Curr Opin Pharmacol

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