One-year ad libitum consumption of diacylglycerol oil as part of a regular diet results in modest weight loss in comparison with consumption of a triacylglycerol control oil in overweight Japanese subjects.

One-year ad libitum consumption of diacylglycerol oil as part of a regular diet results in modest weight loss in comparison with consumption of a triacylglycerol control oil in overweight Japanese subjects. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

One-year ad libitum consumption of diacylglycerol oil as part of a regular diet results in modest weight loss in comparison with consumption of a triacylglycerol control oil in overweight Japanese subjects. Abstract Text:

Hidetoshi Kawashima,Hideto Takase,Koichi Yasunaga,Yoko Wakaki,Yoshihisa Katsuragi,Kenta Mori,Tohru Yamaguchi,Tadashi Hase,Noboru Matsuo,Takuji Yasukawa,Ichiro Tokimitsu,Wasaku Koyama,Hidetoshi Kawashima,Hideto Takase,Koichi Yasunaga,Yoko Wakaki,Yoshihisa Katsuragi,Kenta Mori,Tohru Yamaguchi,Tadashi Hase,Noboru Matsuo,Takuji Yasukawa,Ichiro Tokimitsu,Wasaku Koyama,Hidetoshi Kawashima,Hideto Takase,Koichi Yasunaga,Yoko Wakaki,Yoshihisa Katsuragi,Kenta Mori,Tohru Yamaguchi,Tadashi Hase,Noboru Matsuo,Takuji Yasukawa,Ichiro Tokimitsu,Wasaku Koyama,

OBJECTIVE: The objective of this study was to investigate the effect of 1-year ad libitum consumption of diacylglycerol oil on body weight and serum triglyceride in Japanese men and women. DESIGN/SUBJECTS/INTERVENTION: In a 1-year double-blind, placebo-controlled parallel trial with clinic visits at month 0, 3, 6, 9, and 12, a total of 312 Japanese men (n=174) and women (n=138) (aged 22 to 73 years) with body mass index (calculated as kg/m(2)) >/=25 and/or fasting serum triglyceride level >/=150 mg/dL (1.70 mmol/L) (aged 22 to 73 years) were randomly assigned to the diacylglycerol (n=155) or triacylglycerol (n=157) group. Participants substituted their usual home cooking oil with the assigned test oils. MAIN OUTCOME MEASURES: Changes in anthropometrics and serum triglyceride level were monitored at 3-month intervals across a 12-month period. RESULTS: In the intention-to-treat analysis, body weight decreased significantly in the diacylglycerol group when compared to the triacylglycerol group (P=0.013). Changes in body weight and body mass index during the study period differed between the two groups by 0.87 kg (P=0.002) and 0.32 kg (P=0.002), respectively. Participants with higher initial body mass index or greater percentage of total fat intake as diacylglycerol exhibited greater reduction in body weight. Total energy intake and physical activity were not significantly different between the groups during the study. Serum triglyceride levels decreased significantly from values in individuals with hypertriglyceridemia, but did not differ between groups. CONCLUSIONS: Modest body weight reduction was observed after 1-year ad libitum consumption of diacylglycerol oil as part of a regular diet in comparison to that of triacylglycerol oil; weight loss was greatest in participants who were obese at baseline. The weight reduction observed in diacylglycerol group was attributed to the substitution of usual home cooking oil with diacylglycerol, because total energy intake and physical activity did not differ between groups.

One-year ad libitum consumption of diacylglycerol oil as part of a regular diet results in modest weight loss in comparison with consumption of a triacylglycerol control oil in overweight Japanese subjects. Publishing Authors By Initials

H Kawashima,H Takase,K Yasunaga,Y Wakaki,Y Katsuragi,K Mori,T Yamaguchi,T Hase,N Matsuo,T Yasukawa,I Tokimitsu,W Koyama,H Kawashima,H Takase,K Yasunaga,Y Wakaki,Y Katsuragi,K Mori,T Yamaguchi,T Hase,N Matsuo,T Yasukawa,I Tokimitsu,W Koyama,H Kawashima,H Takase,K Yasunaga,Y Wakaki,Y Katsuragi,K Mori,T Yamaguchi,T Hase,N Matsuo,T Yasukawa,I Tokimitsu,W Koyama,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

One-year ad libitum consumption of diacylglycerol oil as part of a regular diet results in modest weight loss in comparison with consumption of a triacylglycerol control oil in overweight Japanese subjects. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of the American Dietetic Association

VOLUME: 108

Page Numbers: 57-66

Journal Abbreviation:

ISSN: 0002-8223

DAY: 24

MONTH: Jan

YEAR: 2008

One-year ad libitum consumption of diacylglycerol oil as part of a regular diet results in modest weight loss in comparison with consumption of a triacylglycerol control oil in overweight Japanese subjects. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7503061

One-year ad libitum consumption of diacylglycerol oil as part of a regular diet results in modest weight loss in comparison with consumption of a triacylglycerol control oil in overweight Japanese subjects. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: One-year ad libitum consumption of diacylglycerol oil as part of a regular diet results in modest weight loss in comparison with consumption of a triacylglycerol control oil in overweight Japanese subjects. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for One-year ad libitum consumption of diacylglycerol oil as part of a regular diet results in modest weight loss in comparison with consumption of a triacylglycerol control oil in overweight Japanese subjects.

AFFILIATION:

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Am Diet Assoc

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

One-year ad libitum consumption of diacylglycerol oil as part of a regular diet results in modest weight loss in comparison with consumption of a triacylglycerol control oil in overweight Japanese subjects Related Publications

• A case of anorexia nervosa with Marchiafava-Bignami Disease that responded to high-dose intravenous corticosteroid administration.
• A histotopographic study of the perineal body in elderly women: the surgical applicability of novel histological findings.
• A solution to the controversy between rate and temporal coding.
• Bone morphogenetic protein-2 counterregulates interleukin-18 mRNA and protein in MC3T3-E1 mouse osteoblastic cells.
• Characterization of AtALMT1 expression in aluminum-inducible malate release and its role for rhizotoxic stress tolerance in Arabidopsis.
• Conjugation-Length Dependence of the T(1) Lifetimes of Carotenoids Free in Solution and Incorporated into the LH2, LH1, RC, and RC-LH1 Complexes: Possible Mechanisms of Triplet-Energy Dissipation.
• Endoscopic pancreatic duct drainage and stenting for acute pancreatitis and pancreatic cyst and abscess.
• Evaluation of bioprosthetic valve for small aortic root in elderly patients.
• Hepatocyte dynamics in a three-dimensional rotating bioreactor.
• Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.
• Immunoglobulin production against Staphylococcal adhesin and polyclonal immunoglobulin activation induced by superantigen.
• Management of meconium-related ileus in very low-birthweight infants.
• Natural variation of Arabidopsis thaliana reveals that aluminum resistance and proton resistance are controlled by different genetic factors.
• Neonatally born granule cells numerically dominate adult mice dentate gyrus.
• Persistent responsiveness of long-latency auditory cortical activities in response to repeated stimuli of musical timbre and vowel sounds.
• Serum p53 antibodies as an early detection marker in colorectal cancer.
• Significance of Asn-77 and Trp-78 in the catalytic function of undecaprenyl diphosphate synthase of Micrococcus luteus B-P 26.
• Social cognitive impairment in Parkinson's disease.
• Study of transcripts from AC010088, a 199,485 bp fragment of the human Y chromosome located in the azoospermia factor region c.
• Substrate specificities of wild and mutated farnesyl diphosphate synthases from Bacillus stearothermophilus with artificial substrates.
• Synergistic effects of tandospirone and selective serotonin reuptake inhibitors on the contextual conditioned fear stress response in rats.
• Temporomandibular joint formation and condyle growth require Indian hedgehog signaling.
• The SCFCdc4 ubiquitin ligase regulates calcineurin signaling through degradation of phosphorylated Rcn1, an inhibitor of calcineurin.
• Transaminase of branched chain amino acids. I. Branched chain amino acids-alpha-ketoglutarate transaminase.
• Usefulness of perioperative blood glucose control in patients undergoing off-pump coronary artery bypass grafting.
• [Clinical relevance of antidepressant-induced activation syndrome: from a perspective of bipolar spectrum disorder]
• [Disseminated intravascular coagulation (DIC)]
• [Evaluation of the effectiveness of gonad protection in diagnostic radiology]
• [Hypertension in general anesthesia]
• [Nephrotic syndrome]