A highly enantioselective (S)-diphenylpyrrolinol triethylsilyl ether promoted tandem oxa-Michael-aldol reaction of alpha,beta-unsaturated aldehydes with salicylaldehydes has been developed; the method affords one-pot access to chiral and synthetically useful chromenes in high yields and high enantioselectivities from readily available compounds.
One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction. Publishing Authors By Initials
One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction. Journal Published:
PUBLICATION TYPE: Research Support, Non-U.S. Gov
Journal: Chemical communications (Cambridge, England)
VOLUME:
Page Numbers: 507-9
Journal Abbreviation: Chem. Commun. (Camb.)
ISSN: 1359-7345
DAY: 1
MONTH: 11
YEAR: 2006
One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 9610838
One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction. Keywords Mesh Terms:
KEYWORDS: Stereoisomerism
MESH TERMS: methods
Chemical & Substance for Abstract: One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction. Information
Substance Name: salicylaldehyde
Registry Number: 90-02-8
Grant and Affiliation Information for One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction.
AFFILIATION: Department of Chemistry, University of New Mexico, Albuquerque, NM 87131, USA.
Country: England
AGENCY: United States NCRR
GRANT: P20 RR016480
ACRONYM: RR
MEDLINETA: Chem Commun (Camb)
REFSOURCE: Chem Commun (Camb). 2007 Feb 28;(8):878
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ACCESSION NUMBER:
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