On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights.

On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights. Abstract Text:

Chaomin Li,Collin Chan,Annekatrin C Heimann,Samuel J Danishefsky,

On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights. Publishing Authors By Initials

C Li,C Chan,AC Heimann,SJ Danishefsky,

For similar natural sciences: chemistry: chemistry, organic: isomerism: stereoisomerism research abstracts see: natural sciences: chemistry: chemistry, organic: isomerism: stereoisomerism research

PUBMED ID PMID:

MEDLINE DATE:

On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Angewandte Chemie (International ed. in English)

VOLUME: 46

Page Numbers: 1444-7

Journal Abbreviation: Angew. Chem. Int. Ed. Engl.

ISSN: 1433-7851

DAY: 3

MONTH: 12

YEAR: 2007

On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370543

On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights. Keywords Mesh Terms:

KEYWORDS: Stereoisomerism

MESH TERMS: chemistry

Chemical & Substance for Abstract: On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights. Information

Substance Name: Indoles

Registry Number: 0

Grant and Affiliation Information for On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights.

AFFILIATION: The Department of Chemistry, Columbia University, Havemeyer Hall, New York, NY 10027, USA.

Country: Germany

AGENCY: United States NHLBI

GRANT: HL25848

ACRONYM: HL

MEDLINETA: Angew Chem Int Ed Engl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights Related Publications

• A potentially valuable advance in the synthesis of carbohydrate-based anticancer vaccines through extended cycloaddition chemistry.
• A total synthesis of xestodecalactone a and proof of its absolute stereochemistry: interesting observations on dienophilic control with 1,3-disubstituted nonequivalent allenes.
• An interesting issue of Diels-Alder selectivity discovered en route to 11-O-debenzoyltashironin.
• Applications of total synthesis to problems in neurodegeneration: Fascinating chemistry along the way.
• Building complex glycopeptides: Development of a cysteine-free native chemical ligation protocol.
• Chemical synthesis of normal and transformed PSA glycopeptides.
• Complex target-oriented total synthesis in the drug discovery process: the discovery of a highly promising family of second generation epothilones.
• Conformational locking through allylic strain as a device for stereocontrol--total synthesis of grandisine A.
• Creating quaternary centers with high exo stereoselectivity using activated alpha-alkynyl dienophiles.
• Development of efficient methods for accomplishing cysteine-free peptide and glycopeptide coupling.
• Differentiation of nonconventional "carbanions"-the total synthesis of nemorosone and clusianone.
• Discovery of potent cell migration inhibitors through total synthesis: lessons from structure-activity studies of (+)-migrastatin.
• Free-radical-based, specific desulfurization of cysteine: a powerful advance in the synthesis of polypeptides and glycopolypeptides.
• Fully synthetic carbohydrate HIV antigens designed on the logic of the 2G12 antibody.
• On the rearrangement of an azaspiroindolenine to a precursor to phalarine: mechanistic insights.
• Studies related to the relative thermodynamic stability of C-terminal peptidyl esters of O-hydroxy thiophenol: emergence of a doable strategy for non-cysteine ligation applicable to the chemical synthesis of glycopeptides.
• The total synthesis of (+)-migrastatin.
• The total synthesis of (+/-)-11-O-debenzoyltashironin.
• The total synthesis of spirotenuipesines A and B.
• Total synthesis of (+)-isomigrastatin.
• Total synthesis of (+)-suaveolindole: establishment of its absolute configuration.
• Total synthesis of (+/-)-jiadifenin, a non-peptidyl neurotrophic modulator.
• Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production.
• Total synthesis of cribrostatin IV: fine-tuning the character of an amide bond by remote control.
• Total synthesis of paecilomycine A.
• Total synthesis of peribysin E necessitates revision of the assignment of its absolute configuration.
• Total synthesis of phalarine.
• Total synthesis of salinosporamide A.
• Toward fully synthetic carbohydrate-based HIV antigen design: on the critical role of bivalency.
• Toward fully synthetic glycoproteins by ultimately convergent routes: a solution to a long-standing problem.