On the accuracy of techniques for obtaining the calibration coefficient N(K) of 192Ir HDR brachytherapy sources.

On the accuracy of techniques for obtaining the calibration coefficient N(K) of 192Ir HDR brachytherapy sources. Research Abstract Details 

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On the accuracy of techniques for obtaining the calibration coefficient N(K) of 192Ir HDR brachytherapy sources. Abstract Text:

Ernesto Mainegra-Hing,D W O Rogers,

The accuracy of interpolation or averaging procedures for obtaining the calibration coefficient N(K) for 192Ir high-dose-rate brachytherapy sources has been investigated using the EGSnrc Monte Carlo simulation system. It is shown that the widely used two-point averaging procedure of Goetsch et al. [Med. Phys. 18, 462 (1991)] has some conceptual problems. Most importantly, they recommended, as did the IAEA, averaging A(wall)N(K) values whereas one should average 1/N(K) values. In practice this and other issues are shown to have little effect except for Goetsch et al.'s methods for determining A(wall) values. Their method of generalizing the A(wall) values measured in one geometry to other geometries is incorrect by up to 2%. However, these errors in A(wall) values cause systematic errors of only 0.3% in 192Ir calibration coefficients. It is shown that A(wall) values need not be included in the averaging technique at all, thereby simplifying the technique considerably. It is demonstrated that as long as ion chambers with a flat response are used and/or very heavily filtered 250 kV (or higher) beams of x rays are used in the averaging, then almost all techniques can provide adequate accuracy.

On the accuracy of techniques for obtaining the calibration coefficient N(K) of 192Ir HDR brachytherapy sources. Publishing Authors By Initials

E Mainegra-Hing,DW Rogers,

For similar investigative techniques: epidemiologic methods: statistics as topic: sensitivity and specificity research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: sensitivity and specificity research

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On the accuracy of techniques for obtaining the calibration coefficient N(K) of 192Ir HDR brachytherapy sources. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Medical physics

VOLUME: 33

Page Numbers: 3340-7

Journal Abbreviation:

ISSN: 0094-2405

DAY: 3

MONTH: Sep

YEAR: 2006

On the accuracy of techniques for obtaining the calibration coefficient N(K) of 192Ir HDR brachytherapy sources. Information

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LANGUAGE: eng

NlmUniqueID: 425746

On the accuracy of techniques for obtaining the calibration coefficient N(K) of 192Ir HDR brachytherapy sources. Keywords Mesh Terms:

KEYWORDS: Sensitivity and Specificity

MESH TERMS: standards

Chemical & Substance for Abstract: On the accuracy of techniques for obtaining the calibration coefficient N(K) of 192Ir HDR brachytherapy sources. Information

Substance Name: Iridium Radioisotopes

Registry Number: 0

Grant and Affiliation Information for On the accuracy of techniques for obtaining the calibration coefficient N(K) of 192Ir HDR brachytherapy sources.

AFFILIATION: Ionizing Radiation Standards, National Research Council of Canada, Ottawa K1A 0R6, Canada.

Country: United States

AGENCY: United States NCI

GRANT: R01 CA66852

ACRONYM: CA

MEDLINETA: Med Phys

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