On mobility analysis of functional sites from time lapse microscopic image sequences of living cell nucleus.

On mobility analysis of functional sites from time lapse microscopic image sequences of living cell nucleus. Research Abstract Details 

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On mobility analysis of functional sites from time lapse microscopic image sequences of living cell nucleus. Abstract Text:

Lopamudra Mukherjee,Vikas Singh,Jinhui Xu,Kishore S Malyavantham,Ronald Berezney,

Recent research in biology has indicated correlations between the movement patterns of functional sites (such as replication sites in DNA) and zones of genetic activity within a nucleus. A detailed study and analysis of the motion dynamics of these sites can reveal an interesting insight into their role in DNA replication and function. In this paper, we propose a suite of novel techniques to determine, analyze, and interpret the mobility patterns of functional sites. Our algorithms are based on interesting ideas from theoretical computer science and database theory and provide for the first time the tools to interpret the seemingly stochastic motion patterns of the functional sites within the nucleus in terms of a set of tractable 'patterns' which can then be analyzed to understand their biological significance.

On mobility analysis of functional sites from time lapse microscopic image sequences of living cell nucleus. Publishing Authors By Initials

L Mukherjee,V Singh,J Xu,KS Malyavantham,R Berezney,

For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: subtraction technique research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: subtraction technique research

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On mobility analysis of functional sites from time lapse microscopic image sequences of living cell nucleus. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Medical image computing and computer-assisted inte

VOLUME: 9

Page Numbers: 577-85

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ISSN:

DAY: 3

MONTH: 12

YEAR: 2006

On mobility analysis of functional sites from time lapse microscopic image sequences of living cell nucleus. Information

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LANGUAGE: eng

NlmUniqueID: 101249582

On mobility analysis of functional sites from time lapse microscopic image sequences of living cell nucleus. Keywords Mesh Terms:

KEYWORDS: Subtraction Technique

MESH TERMS: methods

Chemical & Substance for Abstract: On mobility analysis of functional sites from time lapse microscopic image sequences of living cell nucleus. Information

Substance Name: DNA

Registry Number: 9007-49-2

Grant and Affiliation Information for On mobility analysis of functional sites from time lapse microscopic image sequences of living cell nucleus.

AFFILIATION: Department of Computer Science and Engineering, State University of New York at Buffalo, USA. lm37@cse.buffalo.edu

Country: Germany

AGENCY: United States NIGMS

GRANT: GM 072131-23

ACRONYM: GM

MEDLINETA: Med Image Comput Comput Assist

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