Oligoclonal T cell expansion in blood but not in the thymus from a patient with thymoma-associated pure red cell aplasia.

Oligoclonal T cell expansion in blood but not in the thymus from a patient with thymoma-associated pure red cell aplasia. Research Abstract Details 

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Oligoclonal T cell expansion in blood but not in the thymus from a patient with thymoma-associated pure red cell aplasia. Abstract Text:

Naohito Fujishima,Makoto Hirokawa,Masumi Fujishima,Chizu Wada,Itaru Toyoshima,Sumio Watanabe,Ken-ichi Sawada,

Despite the well-known association between thymoma and PRCA, the role of thymoma remains uncertain. There is accumulating evidence that clonal T cells are involved in acquired PRCA. We examined T cell receptor repertoires in blood and thymus from a patient with PRCA associated with thymoma and myasthenia gravis. Oligoclonal expansions of Vdelta1- and Vbeta1-expressing T cells were found in peripheral blood, whereas the repertoires of Vdelta1+ and Vbeta1+ T cells in thymoma were not skewed. Oligoclonal expansion of Vdelta1-expressing T cells remained unchanged after thymectomy. Thymus may not be the site of clonal T cell expansion in thymoma-associated PRCA.

Oligoclonal T cell expansion in blood but not in the thymus from a patient with thymoma-associated pure red cell aplasia. Publishing Authors By Initials

N Fujishima,M Hirokawa,M Fujishima,C Wada,I Toyoshima,S Watanabe,K Sawada,

For similar neoplasms: neoplasms by site: thoracic neoplasms: thymus neoplasms research abstracts see: neoplasms: neoplasms by site: thoracic neoplasms: thymus neoplasms research

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Oligoclonal T cell expansion in blood but not in the thymus from a patient with thymoma-associated pure red cell aplasia. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Haematologica

VOLUME: 91

Page Numbers: ECR47

Journal Abbreviation: Haematologica

ISSN: 1592-8721

DAY: 29

MONTH: Dec

YEAR: 2006

Oligoclonal T cell expansion in blood but not in the thymus from a patient with thymoma-associated pure red cell aplasia. Information

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LANGUAGE: eng

NlmUniqueID: 417435

Oligoclonal T cell expansion in blood but not in the thymus from a patient with thymoma-associated pure red cell aplasia. Keywords Mesh Terms:

KEYWORDS: Thymus Neoplasms

MESH TERMS: surgery

Chemical & Substance for Abstract: Oligoclonal T cell expansion in blood but not in the thymus from a patient with thymoma-associated pure red cell aplasia. Information

Substance Name: Cyclosporine

Registry Number: 59865-13-3

Grant and Affiliation Information for Oligoclonal T cell expansion in blood but not in the thymus from a patient with thymoma-associated pure red cell aplasia.

AFFILIATION: Division of Hematology and Oncology, Department of Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita Japan. naofuji@doc.med.akita-u.ac.jp

Country: Italy

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MEDLINETA: Haematologica

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