Off-line fractional exhaled nitric oxide measurement is useful to screen allergic airway inflammation in an adult population.

Off-line fractional exhaled nitric oxide measurement is useful to screen allergic airway inflammation in an adult population. Research Abstract Details 

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Off-line fractional exhaled nitric oxide measurement is useful to screen allergic airway inflammation in an adult population. Abstract Text:

Junpei Saito,Suguru Sato,Hideki Hasunuma,Yasushi Ishimaru,Hiroshi Kanegae,Shoji Kudo,Mitsuru Munakata,Junpei Saito,Suguru Sato,Hideki Hasunuma,Yasushi Ishimaru,Hiroshi Kanegae,Shoji Kudo,Mitsuru Munakata,Junpei Saito,Suguru Sato,Hideki Hasunuma,Yasushi Ishimaru,Hiroshi Kanegae,Shoji Kudo,Mitsuru Munakata,

To determine whether off-line fractional exhaled nitric oxide (FeNO) measurement is applicable to screen allergic airway inflammation for epidemiologic studies, we examined 280 adults, measuring off-line FeNO samplings, pulmonary function, and serum immunoglobulin E (IgE). Subjects with recurrent wheeze (recurrent wheezers) had significantly higher FeNO and IgE levels and significantly lower forced expiratory volume in 1 second/forced vital capacity (FEV(1)/FVC) than non-wheezers. Statistical analysis showed that FeNO and FEV(1)/FVC were significant predictors for recurrent wheezers, independent of smoking. The cut-off FeNO level for screening allergic airway inflammation was 38 ppb in non-smokers and 32.9 ppb in smokers. Thus, off-line FeNO can be used as a good marker to screen allergic airway inflammation, regardless of smoking.

Off-line fractional exhaled nitric oxide measurement is useful to screen allergic airway inflammation in an adult population. Publishing Authors By Initials

J Saito,S Sato,H Hasunuma,Y Ishimaru,H Kanegae,S Kudo,M Munakata,J Saito,S Sato,H Hasunuma,Y Ishimaru,H Kanegae,S Kudo,M Munakata,J Saito,S Sato,H Hasunuma,Y Ishimaru,H Kanegae,S Kudo,M Munakata,

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Off-line fractional exhaled nitric oxide measurement is useful to screen allergic airway inflammation in an adult population. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of asthma : official journal of the As

VOLUME: 44

Page Numbers: 805-10

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ISSN: 1532-4303

DAY: 21

MONTH: Dec

YEAR: 2007

Off-line fractional exhaled nitric oxide measurement is useful to screen allergic airway inflammation in an adult population. Information

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LANGUAGE: eng

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AFFILIATION: Department of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, Japan.

Country: United States

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MEDLINETA: J Asthma

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