Off-line automated sample preparation-experience in a clinical drug investigation unit.

Off-line automated sample preparation-experience in a clinical drug investigation unit. Research Abstract Details 

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Off-line automated sample preparation-experience in a clinical drug investigation unit. Abstract Text:

S J McIntosh,I D Watson,P W Hughes,A M Chambers,M J Stewart,

The authors describe an evaluation of the Du Pont Prep. off-line automatic centrifugal sample processing system, used in the authors' Drug Investigation Unit over the past two years. In comparison to liquid-liquid extraction, the authors found that assay precision has generally been improved, absolute recovery was quantitative, reliability has been good and the use of the system has resulted in notable labour saving. However, the cost per test based on a seven-year amortization of capital cost shows that the system is more expensive. Assays for urinary opiates, serum tricyclic antidepressants, serum isoxicam, serum valproate, serum metoclopramide and serum pindolol are presented and the merits of the method are compared with those for manual liquid-liquid extraction procedures.

Off-line automated sample preparation-experience in a clinical drug investigation unit. Publishing Authors By Initials

SJ McIntosh,ID Watson,PW Hughes,AM Chambers,MJ Stewart,

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Off-line automated sample preparation-experience in a clinical drug investigation unit. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of pharmaceutical and biomedical analysis

VOLUME: 5

Page Numbers: 353-60

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ISSN: 0731-7085

DAY: 26

MONTH: 07

YEAR: 1987

Off-line automated sample preparation-experience in a clinical drug investigation unit. Information

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LANGUAGE: eng

NlmUniqueID: 8309336

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Grant and Affiliation Information for Off-line automated sample preparation-experience in a clinical drug investigation unit.

AFFILIATION: Drug Investigation Unit, Department of Biochemistry, Royal Infirmary, Glasgow G4 0SF, UK.

Country: England

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MEDLINETA: J Pharm Biomed Anal

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