Occurrence of hepatitis B-surface antigen in a consecutive material of 1539 liver biopsies.

Occurrence of hepatitis B-surface antigen in a consecutive material of 1539 liver biopsies. Research Abstract Details 

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Occurrence of hepatitis B-surface antigen in a consecutive material of 1539 liver biopsies. Abstract Text:

The frequency and occurrence of hepatitis B-surface antigen (HBsAg) in 1539 consecutive liver biopsies were determined using orcein staining as screening method. In HBsAg seropositive cases sections were in addition stained with immunoperoxidase staining for HBsAg in order to reassure the presence of HBsAg in liver cells. HBsAg was demonstrated in 36 biopsies (2.3%). The highest frequency was found in biopsies with chronic hepatitis (28%). In biopsies with slight non-specific changes 10% and in cirrhotic 4.5% contained HBsAg. HBsAg was not detected in biopsies with acute hepatitis. No correlation was found between the number of HBsAg containing cells in the biopsies and the histological/biochemical activity in the liver. It is concluded that orcein staining of ground-glass appearance is a highly specific HBsAg marker. The sensitivity is about 80% in cases with minimal changes, chronic hepatitis and cirrhosis. The method is unsuitable as etiological marker in cases with acute hepatitis.

Occurrence of hepatitis B-surface antigen in a consecutive material of 1539 liver biopsies. Publishing Authors By Initials

For similar heterocyclic compounds: heterocyclic compounds, 1-ring: oxazines research abstracts see: heterocyclic compounds: heterocyclic compounds, 1-ring: oxazines research

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Occurrence of hepatitis B-surface antigen in a consecutive material of 1539 liver biopsies. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta pathologica, microbiologica, et immunologica

VOLUME: 91

Page Numbers: 71-5

Journal Abbreviation:

ISSN: 0108-0164

DAY: 26

MONTH: Jan

YEAR: 1983

Occurrence of hepatitis B-surface antigen in a consecutive material of 1539 liver biopsies. Information

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LANGUAGE: eng

NlmUniqueID: 8206622

Occurrence of hepatitis B-surface antigen in a consecutive material of 1539 liver biopsies. Keywords Mesh Terms:

KEYWORDS: Oxazines

MESH TERMS: immunology

Chemical & Substance for Abstract: Occurrence of hepatitis B-surface antigen in a consecutive material of 1539 liver biopsies. Information

Substance Name: PAcein

Registry Number: 1400-62-0

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Country: DENMARK

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MEDLINETA: Acta Pathol Microbiol Immunol

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