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Nucleotide sequence of the promoter region of chicken cytosolic phosphoenolpyruvate carboxykinase gene.

Nucleotide sequence of the promoter region of chicken cytosolic phosphoenolpyruvate carboxykinase gene. Research Abstract Details 

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  • Nucleotide sequence of the promoter region of chicken cytosolic phosphoenolpyruvate carboxykinase gene. Abstract Text:

    a satoA Sato,h takahashiH Takahashi,k konishiK Konishi,t suzukiT Suzuki,h kochiH Kochi,

    The nucleotide sequence of the promoter region and its flanking regions which span - 1855 to +2083 in the chicken cytosolic phosphoenolpyruvate carboxykinase gene was determined. The transcription initiation site was located at 119 nucleotides downstream of the previously reported chicken kidney transcription initiation site of this gene. The nucleotide sequences of exons 1, 2, and 3 were highly homologous to the corresponding exons of the rat gene. Homology of the sequence - 1 to - 500 to that of rat gene was 52% and most of the hormone-responsive sequences in rat gene, such as the glucocorticoid-responsive region, were not conserved in the chicken gene, in accord with the species-specific responsiveness to starvation. In contrast, in the region of - 1 to - 300, some sequence motifs conserved both in the chicken and rat genes were found at essentially the same positions in the promoters. Such sequence motifs included a cAMP-responsive element (CRE), a nuclear factor-1 (NF-1/CTF)-binding site, and a hepatocyte nuclear factor-1 (HNF-1)-binding site. Transient expression of the reporter luciferase gene ligated to the 3' end of this chicken sequence (-1855 to +7) was observed in a primary culture of chick hepatocytes when dibutyryl cyclic AMP was added to the culture medium.

    Nucleotide sequence of the promoter region of chicken cytosolic phosphoenolpyruvate carboxykinase gene. Publishing Authors By Initials

    a satoA Sato,h takahashiH Takahashi,k konishiK Konishi,t suzukiT Suzuki,h kochiH Kochi,

    For similar proteins: dna-binding proteins: basic-leucine zipper transcription factors: ccaat-enhancer-binding proteins: y-box-binding protein 1 research abstracts see: proteins: dna-binding proteins: basic-leucine zipper transcription factors: ccaat-enhancer-binding proteins: y-box-binding protein 1 research

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    Nucleotide sequence of the promoter region of chicken cytosolic phosphoenolpyruvate carboxykinase gene. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Journal of biochemistry

    VOLUME: 121

    Page Numbers: 711-6

    Journal Abbreviation: J. Biochem.

    ISSN: 0021-924X

    DAY: 19

    MONTH: Apr

    YEAR: 1997

    Nucleotide sequence of the promoter region of chicken cytosolic phosphoenolpyruvate carboxykinase gene. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 376600

    Nucleotide sequence of the promoter region of chicken cytosolic phosphoenolpyruvate carboxykinase gene. Keywords Mesh Terms:

    KEYWORDS: Y-Box-Binding Protein 1

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: Nucleotide sequence of the promoter region of chicken cytosolic phosphoenolpyruvate carboxykinase gene. Information

    Substance Name: Phosphoenolpyruvate Carboxykinase (GTP)

    Registry Number: EC 4.1.1.32

    Grant and Affiliation Information for Nucleotide sequence of the promoter region of chicken cytosolic phosphoenolpyruvate carboxykinase gene.

    AFFILIATION: Information Science Major, Faculty of Liberal Arts, Tohoku-Gakuin University, Izumi-ku, Sendai. asato@izcc.tohoku-gakuin.ac.jp

    Country: JAPAN

    JAPAN Research PublicationJAPAN Research Publication

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    MEDLINETA: J Biochem

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