Novel targets for antibiotics in Staphylococcus aureus.

Novel targets for antibiotics in Staphylococcus aureus. Research Abstract Details 

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Novel targets for antibiotics in Staphylococcus aureus. Abstract Text:

Knut Ohlsen,Udo Lorenz,Knut Ohlsen,Udo Lorenz,

Multiple resistant staphylococci that cause significant morbidity and mortality are the leading cause of nosocomial infections. Meanwhile, methicillin-resistant Staphylococcus aureus (MRSA) also spreads in the community, where highly virulent strains infect children and young adults who have no predisposing risk factors. Although some treatment options remain, the search for new antibacterial targets and lead compounds is urgently required to ensure that staphylococcal infections can be effectively treated in the future. Promising targets for new antibacterials are gene products that are involved in essential cell functions. In addition to antibacterials, active and passive immunization strategies are being developed that target surface components of staphylococci such as cell wall-linked adhesins, teichoic acids and capsule or immunodominant antigens.

Novel targets for antibiotics in Staphylococcus aureus. Publishing Authors By Initials

K Ohlsen,U Lorenz,K Ohlsen,U Lorenz,

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Novel targets for antibiotics in Staphylococcus aureus. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Future microbiology

VOLUME: 2

Page Numbers: 655-66

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ISSN: 1746-0921

DAY: 28

MONTH: Dec

YEAR: 2007

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LANGUAGE: eng

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AFFILIATION: University of Würzburg, Institute for Molecular Infection Biology, Röntgenring 11, 97070 Würzburg, Germany. knut.ohlsen@mail.uni-wuerzburg.de

Country: England

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MEDLINETA: Future Microbiol

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