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Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin.

Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin. Research Abstract Details 

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  • Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin. Abstract Text:

    Twenty-two veterans with posttraumatic stress disorder (PTSD) were assessed for trauma-related nightmares and nonnightmare distressed awakenings (NNDA) before and after treatment with the alpha-1 adrenoreceptor antagonist prazosin at an average bedtime dose of 9.6 mg/day. Ratings combining frequency and intensity dimensions of trauma-related nightmares decreased from 3.6 to 2.2, NNDA from 5.2 to 2.1, and sleep difficulty from 7.2 to 4.1 per week. These results suggest that increased brain adrenergic activity may contribute to the pathophysiology of both trauma-related nightmares and NNDA in PTSD.

    Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin. Publishing Authors By Initials

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    PUBMED ID PMID:

    MEDLINE DATE:

    Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin. Journal Published:

    PUBLICATION TYPE: Research Support, U.S. Gov't,

    Journal: Journal of traumatic stress

    VOLUME: 21

    Page Numbers: 417-20

    Journal Abbreviation:

    ISSN: 1573-6598

    DAY: 28

    MONTH: Aug

    YEAR: 2008

    Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8809259

    Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin. Keywords Mesh Terms:

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    Chemical & Substance for Abstract: Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin. Information

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    Grant and Affiliation Information for Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin.

    AFFILIATION: VA Northwest Network, Mental Illness Research, Education and Clinical Center, Seattle, WA 98108, USA.

    Country: United States

    United States Research PublicationUnited States Research Publication

    AGENCY: United States NIMH

    GRANT: R01 MH069867

    ACRONYM: MH

    MEDLINETA: J Trauma Stress

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    Number Hits: 0

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