Noncanonical cell death pathways act during Drosophila oogenesis.

Noncanonical cell death pathways act during Drosophila oogenesis. Research Abstract Details 

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Noncanonical cell death pathways act during Drosophila oogenesis. Abstract Text:

Jeanne S Peterson,B Paige Bass,Deborah Jue,Antony Rodriguez,John M Abrams,Kimberly McCall,

Programmed cell death (PCD) is a highly conserved process that occurs during development and in response to adverse conditions. In Drosophila, most PCDs require the genes within the H99 deficiency, the adaptor molecule Ark, and caspases. Here we investigate 10 cell death genes for their potential roles in two distinct types of PCD that occur in oogenesis: developmental nurse cell PCD and starvation-induced PCD. Most of the genes investigated were found to have little effect on late stage developmental PCD in oogenesis, although ark mutants showed a partial inhibition. Mid-stage starvation-induced germline PCD was found to be independent of the upstream activators and ark although it requires caspases, suggesting an apoptosome-independent mechanism of caspase activation in mid-oogenesis. These results indicate that novel pathways must control PCD in the ovary.

Noncanonical cell death pathways act during Drosophila oogenesis. Publishing Authors By Initials

JS Peterson,BP Bass,D Jue,A Rodriguez,JM Abrams,K McCall,

For similar biological phenomena, cell phenomena, and immunity: cell physiology: cell communication: signal transduction research abstracts see: biological phenomena, cell phenomena, and immunity: cell physiology: cell communication: signal transduction research

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Noncanonical cell death pathways act during Drosophila oogenesis. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Genesis (New York, N.Y. : 2000)

VOLUME: 45

Page Numbers: 396-404

Journal Abbreviation: Genesis

ISSN: 1526-954X

DAY: 3

MONTH: Jun

YEAR: 2007

Noncanonical cell death pathways act during Drosophila oogenesis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100931242

Noncanonical cell death pathways act during Drosophila oogenesis. Keywords Mesh Terms:

KEYWORDS: Signal Transduction

MESH TERMS: physiology

Chemical & Substance for Abstract: Noncanonical cell death pathways act during Drosophila oogenesis. Information

Substance Name: Drosophila Proteins

Registry Number: 0

Grant and Affiliation Information for Noncanonical cell death pathways act during Drosophila oogenesis.

AFFILIATION: Department of Biology, Boston University, Boston, Massachusetts 02115, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: R01 GM60574

ACRONYM: GM

MEDLINETA: Genesis

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