No evidence for an association between serum cholesterol and the course of depression and suicidality.

No evidence for an association between serum cholesterol and the course of depression and suicidality. Research Abstract Details 

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No evidence for an association between serum cholesterol and the course of depression and suicidality. Abstract Text:

In a number of previous reports, an association of altered, in most cases lower, serum cholesterol levels with depression, suicidal ideation and current or past suicidal behavior has been suggested. In this investigation, the course of serum cholesterol concentrations was measured in depressed patients during treatment. Ninety-two inpatients with a major depressive episode were included. Serum lipid concentrations were assessed at admission, after 1 week and after 4 weeks of antidepressant treatment. Degrees of depression and suicidality were measured with the Hamilton Depression Rating Scale. Although there was a significant reduction in depression and suicidality scores, neither a significant change in serum cholesterol levels nor a correlation between cholesterol levels and clinical improvement was found. Further, there were no significant differences in lipid levels between patients with and without a history of attempted suicide. In patients who had used a violent method, there was a trend for lower total cholesterol levels compared to those who had poisoned themselves. The results of this study do not support the hypothesis of an association of serum cholesterol with the course of depression and suicidal ideation. Cholesterol levels do not appear to be an appropriate biological marker for suicidality during the first 4 weeks of treatment in patients with a major depressive episode.

No evidence for an association between serum cholesterol and the course of depression and suicidality. Publishing Authors By Initials

For similar lipids: glycerides: triglycerides research abstracts see: lipids: glycerides: triglycerides research

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No evidence for an association between serum cholesterol and the course of depression and suicidality. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Psychiatry research

VOLUME: 121

Page Numbers: 253-61

Journal Abbreviation: Psychiatry Res

ISSN: 0165-1781

DAY: 1

MONTH: Jan

YEAR: 2004

No evidence for an association between serum cholesterol and the course of depression and suicidality. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7911385

No evidence for an association between serum cholesterol and the course of depression and suicidality. Keywords Mesh Terms:

KEYWORDS: Triglycerides

MESH TERMS: blood

Chemical & Substance for Abstract: No evidence for an association between serum cholesterol and the course of depression and suicidality. Information

Substance Name: Cholesterol

Registry Number: 57-88-5

Grant and Affiliation Information for No evidence for an association between serum cholesterol and the course of depression and suicidality.

AFFILIATION: Department of General Psychiatry, Innsbruck University Hospital, Anichstrasse 35, A-6020, Innsbruck, Austria. eberhard.deisenhammer@uibk.ac.at

Country: Ireland

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MEDLINETA: Psychiatry Res

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