No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population.

No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population. Research Abstract Details 

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No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population. Abstract Text:

Y Ji,K Urakami,Y Adachi,K Nakashima,

Human apolipoprotein A-IV (apoA-IV) is genetically polymorphic, the apoA-IV polymorphism being controlled by two alleles, apoA-IV1 and apoA-IV2. The association between the apoA-IV2 allele and late-onset Alzheimer's disease (LOAD) has been reported in Caucasian populations. We investigated the codon 360 mutation of the apoA-IV gene allele frequency in 173 LOAD and in 158 age-matched control subjects of the Japanese population, and we found that the allele frequency of apoA-IV2 in the Japanese population was very rare and was extremely lower than in Caucasian populations. We conclude that there was no association between apoA-IV genotype and LOAD in the Japanese population. Copyrightz1999S.KargerAG,Basel

No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population. Publishing Authors By Initials

Y Ji,K Urakami,Y Adachi,K Nakashima,

For similar genetic phenomena: variation (genetics): mutation research abstracts see: genetic phenomena: variation (genetics): mutation research

PUBMED ID PMID:

MEDLINE DATE: 1999 Nov-Dec

No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Dementia and geriatric cognitive disorders

VOLUME: 10

Page Numbers: 473-5

Journal Abbreviation: Dement Geriatr Cogn Disord

ISSN: 1420-8008

DAY: 24

MONTH: 03

YEAR: 2008

No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9705200

No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population. Keywords Mesh Terms:

KEYWORDS: Mutation

MESH TERMS: genetics

Chemical & Substance for Abstract: No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population. Information

Substance Name: apolipoprotein A-IV

Registry Number: 0

Grant and Affiliation Information for No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population.

AFFILIATION: Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan.

Country: SWITZERLAND

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MEDLINETA: Dement Geriatr Cogn Disord

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