NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings.

NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings. Research Abstract Details 

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NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings. Abstract Text:

Melissa Getz,Xiaoyan Sun,Anette Casiano-Negroni,Qi Zhang,Hashim M Al-Hashimi,

An increasing number of RNAs are being discovered that perform their functions by undergoing large changes in conformation in response to a variety of cellular signals, including recognition of proteins and small molecular targets, changes in temperature, and RNA synthesis itself. The measurement of NMR residual dipolar couplings (RDCs) in partially aligned systems is providing new insights into the structural plasticity of RNA through combined characterization of large-amplitude collective helix motions and local flexibility in noncanonical regions over a wide window of biologically relevant timescales (

NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings. Publishing Authors By Initials

M Getz,X Sun,A Casiano-Negroni,Q Zhang,HM Al-Hashimi,

For similar natural sciences: physics: thermodynamics research abstracts see: natural sciences: physics: thermodynamics research

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NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings. Journal Published:

PUBLICATION TYPE: Review

Journal: Biopolymers

VOLUME: 86

Page Numbers: 384-402

Journal Abbreviation: Biopolymers

ISSN: 0006-3525

DAY: 3

MONTH: 12

YEAR: 2007

NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings. Information

Number of References: 146

LANGUAGE: eng

NlmUniqueID: 372525

NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings. Keywords Mesh Terms:

KEYWORDS: Thermodynamics

MESH TERMS: chemistry

Chemical & Substance for Abstract: NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings. Information

Substance Name: RNA

Registry Number: 63231-63-0

Grant and Affiliation Information for NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings.

AFFILIATION: Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109, USA.

Country: United States

AGENCY: United States NIAID

GRANT: R01 AI066975-01

ACRONYM: AI

MEDLINETA: Biopolymers

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