Nicotine and hippocampus-dependent learning: implications for addiction.

Nicotine and hippocampus-dependent learning: implications for addiction. Research Abstract Details 

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Nicotine and hippocampus-dependent learning: implications for addiction. Abstract Text:

Thomas J Gould,

Addiction is a complex disorder because many factors contribute to the development and maintenance of addiction. One factor is learning. For example, drug-context associations that develop during drug use could facilitate drug craving upon re-exposure to contexts previously associated with drugs. Additionally, deficits in cognitive processes associated with withdrawal could precipitate relapse in attempts to ameliorate those deficits. Because addiction and learning involve common neural areas and cell signaling cascades, addiction-related changes in processes underlying plasticity may contribute to addiction. This article examines similarities between addiction and learning at the behavioral, neural, and cellular levels, with emphasis on the neural substrates underlying the effects of acute nicotine, chronic nicotine, and withdrawal from chronic nicotine on hippocampus-dependent contextual learning.

Nicotine and hippocampus-dependent learning: implications for addiction. Publishing Authors By Initials

TJ Gould,

For similar disorders of environmental origin: substance-related disorders: tobacco use disorder research abstracts see: disorders of environmental origin: substance-related disorders: tobacco use disorder research

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Nicotine and hippocampus-dependent learning: implications for addiction. Journal Published:

PUBLICATION TYPE: Review

Journal: Molecular neurobiology

VOLUME: 34

Page Numbers: 93-107

Journal Abbreviation: Mol. Neurobiol.

ISSN: 0893-7648

DAY: 3

MONTH: Oct

YEAR: 2006

Nicotine and hippocampus-dependent learning: implications for addiction. Information

Number of References: 168

LANGUAGE: eng

NlmUniqueID: 8900963

Nicotine and hippocampus-dependent learning: implications for addiction. Keywords Mesh Terms:

KEYWORDS: Tobacco Use Disorder

MESH TERMS: physiopathology

Chemical & Substance for Abstract: Nicotine and hippocampus-dependent learning: implications for addiction. Information

Substance Name: Acetylcholine

Registry Number: 51-84-3

Grant and Affiliation Information for Nicotine and hippocampus-dependent learning: implications for addiction.

AFFILIATION: Department of Psychology, Temple University, Philadelphia, PA, USA. tgould@temple.edu

Country: United States

AGENCY: United States NIDA

GRANT: DA017949

ACRONYM: DA

MEDLINETA: Mol Neurobiol

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