New mass-spectrometry-based strategies for lipids.

New mass-spectrometry-based strategies for lipids. Research Abstract Details 

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New mass-spectrometry-based strategies for lipids. Abstract Text:

Giorgis Isaac,Richard Jeannotte,Steven Wynn Esch,Ruth Welti,

In the past dozen years, many new strategies for mass-spectrometry-based analyses of lipids have been developed. Lipidomics has emerged as a comprehensive approach to analysis of lipids from biological systems, and the most-utilized lipidomics methodologies involve electrospray ionization (ESI) sources and triple quadrupole analyzers. While mass spectral techniques for lipid profiling have advanced, challenges in developing uniform data acquisition methods and in handling, storing, and analyzing mass spectral data remain. Investigation of other ionization methods, including matrix-assisted laser desorption/ionization (MALDI) and atmospheric pressure chemical ionization (APCI), has demonstrated that these are useful in specific applications. APCI is particularly amenable to analysis of less polar lipids, and MALDI provides a rapid technology with application for tissue imaging. Time-of-flight secondary ion mass spectrometry (TOF-SIMS) is particularly suited for imaging of tissues and cells.

New mass-spectrometry-based strategies for lipids. Publishing Authors By Initials

G Isaac,R Jeannotte,SW Esch,R Welti,

For similar investigative techniques: chemistry, analytical: mass spectrometry: spectrometry, mass, secondary ion research abstracts see: investigative techniques: chemistry, analytical: mass spectrometry: spectrometry, mass, secondary ion research

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New mass-spectrometry-based strategies for lipids. Journal Published:

PUBLICATION TYPE: Review

Journal: Genetic engineering

VOLUME: 28

Page Numbers: 129-57

Journal Abbreviation: Genet. Eng. (N.Y.)

ISSN: 0196-3716

DAY: 3

MONTH: 12

YEAR: 2007

New mass-spectrometry-based strategies for lipids. Information

Number of References: 182

LANGUAGE: eng

NlmUniqueID: 7907340

New mass-spectrometry-based strategies for lipids. Keywords Mesh Terms:

KEYWORDS: Spectrometry, Mass, Secondary Ion

MESH TERMS: methods

Chemical & Substance for Abstract: New mass-spectrometry-based strategies for lipids. Information

Substance Name: Lipids

Registry Number: 0

Grant and Affiliation Information for New mass-spectrometry-based strategies for lipids.

AFFILIATION: Division of Biology, Ackert Hall, Kansas State University, Manhattan, KS 66506, USA.

Country: United States

AGENCY: United States NCRR

GRANT: P20 RR016475

ACRONYM: RR

MEDLINETA: Genet Eng (N Y)

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