New cytotoxic drugs and targets in oncology.

New cytotoxic drugs and targets in oncology. Research Abstract Details 

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New cytotoxic drugs and targets in oncology. Abstract Text:

New agents in the preclinical and early clinical pipeline (phases I and II) are described and some of the problems associated with their development are reviewed. The article focuses on tubulin poisons such as taxol, topoisomerase inhibitors, such as topotecan, and drugs such as bryostatin 1 and miltefosin, which interfere with specific signal transduction pathways involved in malignant cell growth.

New cytotoxic drugs and targets in oncology. Publishing Authors By Initials

For similar biochemical phenomena, metabolism, and nutrition: biochemical phenomena: molecular structure research abstracts see: biochemical phenomena, metabolism, and nutrition: biochemical phenomena: molecular structure research

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New cytotoxic drugs and targets in oncology. Journal Published:

PUBLICATION TYPE: Review

Journal: Pharmaceutisch weekblad. Scientific edition

VOLUME: 14

Page Numbers: 258-67

Journal Abbreviation:

ISSN: 0167-6555

DAY: 21

MONTH: Aug

YEAR: 1992

New cytotoxic drugs and targets in oncology. Information

Number of References: 72

LANGUAGE: eng

NlmUniqueID: 7907992

New cytotoxic drugs and targets in oncology. Keywords Mesh Terms:

KEYWORDS: Molecular Structure

MESH TERMS: pharmacology

Chemical & Substance for Abstract: New cytotoxic drugs and targets in oncology. Information

Substance Name: Antineoplastic Agents

Registry Number: 0

Grant and Affiliation Information for New cytotoxic drugs and targets in oncology.

AFFILIATION: Hospital/Netherlands Cancer Institute, Amsterdam.

Country: NETHERLANDS

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MEDLINETA: Pharm Weekbl Sci

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