New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation.

New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation. Research Abstract Details 

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New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation. Abstract Text:

Mike Frohn,Han Xu,Xiaoming Zou,Catherine Chang,Michele McElvaine,Matthew H Plant,Min Wong,Philip Tagari,Randall Hungate,Roland W ,Mike Frohn,Han Xu,Xiaoming Zou,Catherine Chang,Michele McElvaine,Matthew H Plant,Min Wong,Philip Tagari,Randall Hungate,Roland W ,

We report the development of the novel N-substituted benzimidazole 11 as a potent and selective human formyl peptide receptor-like 1 (hFPRL1) agonist. This compound and its less active enantiomer 12 were identified as useful tools for studying receptor function in vitro.

New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation. Publishing Authors By Initials

M Frohn,H Xu,X Zou,C Chang,M McElvaine,MH Plant,M Wong,P Tagari,R Hungate,RW ,M Frohn,H Xu,X Zou,C Chang,M McElvaine,MH Plant,M Wong,P Tagari,R Hungate,RW ,

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New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Bioorganic & medicinal chemistry letters

VOLUME: 17

Page Numbers: 6633-7

Journal Abbreviation: Bioorg. Med. Chem. Lett.

ISSN: 0960-894X

DAY: 15

MONTH: 09

YEAR: 2007

New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation. Information

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LANGUAGE: eng

NlmUniqueID: 9107377

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Grant and Affiliation Information for New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation.

AFFILIATION: Chemistry Research and Discovery, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA.

Country: England

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MEDLINETA: Bioorg Med Chem Lett

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