Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia.

Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia. Abstract Text:

Cognitive Behavioral Social Skills Training (CBSST) is a 24-session weekly group therapy intervention to improve functioning in people with schizophrenia. In our prior randomized clinical trial comparing treatment as usual (TAU) with TAU plus group CBSST (Granholm, E., McQuaid, J.R., McClure, F.S., Auslander, L., Perivoliotis, D., Pedrelli, P., Patterson, T., Jeste, D.V., 2005. A randomized controlled trial of cognitive behavioral social skills training for middle-aged and older outpatients with chronic schizophrenia. Am. J. Psychiatry 162, 520-529.), participants with schizophrenia in CBSST showed significantly better functional outcome than participants in TAU. The present study was a secondary analysis of neuropsychological predictors of functional outcome in our prior CBSST trial. We examined (1) whether neuropsychological impairment at baseline moderated functional outcome in CBSST relative to TAU, and (2) whether improvement in neuropsychological abilities mediated improvement in functional outcome in CBSST. Attention, verbal learning/memory, speed of processing, and executive functions were assessed at baseline, end of treatment, and 12-month follow-up. Greater severity of neuropsychological impairment at baseline predicted poorer functional outcome for both treatment groups (nonspecific predictor), but the interaction between severity of neuropsychological impairment and treatment group was not significant (no moderation). Effect sizes for the difference between treatment groups on functional outcome measures at 12-month follow-up were similar for participants with relatively mild (d=.44-.64) and severe (d=.29-.60) neuropsychological impairment. Results also did not support the hypothesis that improvement in neuropsychological abilities mediated improvement in functioning in CBSST. Adding CBSST to standard pharmacologic care, therefore, improved functioning relative to standard care alone, even for participants with severe neuropsychological impairment, and this improvement in functioning was not related to improvement in neuropsychological abilities in CBSST.

Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Schizophrenia research

VOLUME: 100

Page Numbers: 133-43

Journal Abbreviation: Schizophr. Res.

ISSN: 0920-9964

DAY: 28

MONTH: 01

YEAR: 2008

Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8804207

Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia.

AFFILIATION: Veterans Affairs San Diego Healthcare System, United States; Department of Psychiatry, University of California, San Diego, United States.

Country: Netherlands

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Schizophr Res

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia Related Publications

• A lifestyle intervention for older schizophrenia patients with diabetes mellitus: a randomized controlled trial.
• A review of performance-based measures of functional living skills.
• Antipsychotic polypharmacy trends among Medicaid beneficiaries with schizophrenia in San Diego County, 1999-2004.
• Anxiety disorders in a public mental health system: Clinical characteristics and service use patterns.
• Assessment of medication management ability in middle-aged and older adults with bipolar disorder.
• Brain response correlates of decisional capacity in schizophrenia: a preliminary FMRI study.
• Complementary and alternative medicine (CAM) use in geriatric psychiatry clinics.
• Complementary and alternative treatments for late-life depression, anxiety, and sleep disturbance: a review of randomized controlled trials.
• Costs of community-based public mental health services for older adults: variations related to age and diagnosis.
• Cultural formulation with attention to language and cultural dynamics in a mexican psychiatric patient treated in san diego, california.
• Deficits in cue detection and intention retrieval underlie prospective memory impairment in schizophrenia.
• Diagnostic variability for schizophrenia and major depression in a large public mental health care system dataset.
• Enhancing the informed consent process: a conceptual overview.
• Functional adaptation skills training (FAST): a randomized trial of a psychosocial intervention for middle-aged and older patients with chronic psychotic disorders.
• Health-related quality of well-being in chronically hospitalized patients with schizophrenia: comparison with matched outpatients.
• Impact of atypical antipsychotic therapy on leptin, ghrelin, and adiponectin.
• Initiation and use of public mental health services by persons with severe mental illness and limited english proficiency.
• Medication adherence skills training for middle-aged and elderly adults with bipolar disorder: development and pilot study.
• Multivariate predictors of social skills performance in middle-aged and older out-patients with schizophrenia spectrum disorders.
• Neurocognitive functioning in dually diagnosed middle aged and elderly patients with alcoholism and schizophrenia.
• Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia.
• Pharmacotherapy of neuropsychiatric syndromes in neurologic disorders: definitional and regulatory aspects.
• Preliminary report: cerebral blood flow abnormalities in older schizophrenic patients.
• Public-academic partnerships: improving care for older persons with schizophrenia through an academic-community partnership.
• Publication of the International Psychogeriatric Association consensus statement on defining and measuring treatment benefits in dementia.
• Randomized controlled trial of cognitive behavioral social skills training for older people with schizophrenia: 12-month follow-up.
• Recent advances in research on successful or healthy aging.
• Self-administered cognitive screening for a study of successful aging among community-dwelling seniors: a preliminary study.
• Successful aging: from phenotype to genotype.
• Unmet needs for mental health services for latino older adults: perspectives from consumers, family members, advocates, and service providers.