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Neuropharmacological assessment of growth hormone secretion.

Neuropharmacological assessment of growth hormone secretion. Research Abstract Details 

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  • Neuropharmacological assessment of growth hormone secretion. Abstract Text:

    The biochemical diagnosis of individuals who are either deficient in growth hormone (GH) or who have alterations in the normal pattern of GH secretion is difficult. The uncertainty surrounding diagnosis reflects the lack of a thorough understanding of the physiology of GH secretion and of the hypothalamic hormones involved. At least three hormones are implicated: GH-releasing hormone (GHRH), somatostatin and the endogenous ligand of the GH secretagogue receptor, although the role that each plays in the release of GH is not clear from the available experimental evidence. In such a situation, most of the dynamic tests of GH secretory capacity in humans need to undergo a 'trial and error' process before being validated. The search for the 'gold standard' test of GH secretion is ongoing, and the combination of GHRH plus GH secretagogues will probably play an important role in future clinical diagnosis.

    Neuropharmacological assessment of growth hormone secretion. Publishing Authors By Initials

    For similar hormones, hormone substitutes, and hormone antagonists: hormones: peptide hormones: hypothalamic hormones: pituitary hormone release inhibiting hormones: somatostatin research abstracts see: hormones, hormone substitutes, and hormone antagonists: hormones: peptide hormones: hypothalamic hormones: pituitary hormone release inhibiting hormones: somatostatin research

    PUBMED ID PMID:

    MEDLINE DATE:

    Neuropharmacological assessment of growth hormone secretion. Journal Published:

    PUBLICATION TYPE: Review

    Journal: Acta paediatrica (Oslo, Norway : 1992). Supplement

    VOLUME: 423

    Page Numbers: 12-6

    Journal Abbreviation: Acta Paediatr Suppl

    ISSN: 0803-5326

    DAY: 12

    MONTH: Nov

    YEAR: 1997

    Neuropharmacological assessment of growth hormone secretion. Information

    Number of References: 32

    LANGUAGE: eng

    NlmUniqueID: 9315043

    Neuropharmacological assessment of growth hormone secretion. Keywords Mesh Terms:

    KEYWORDS: Somatostatin

    MESH TERMS: physiology

    Chemical & Substance for Abstract: Neuropharmacological assessment of growth hormone secretion. Information

    Substance Name: Growth Hormone-Releasing Hormone

    Registry Number: 9034-39-3

    Grant and Affiliation Information for Neuropharmacological assessment of growth hormone secretion.

    AFFILIATION: Department of Physiology, Complejo Hospitalario de Santiago, Santiago de Compostela University, Spain.

    Country: NORWAY

    NORWAY Research PublicationNORWAY Research Publication

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    ACRONYM:

    MEDLINETA: Acta Paediatr Suppl

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