Neuropeptide Y modulation of ethanol intake: effects of ethanol drinking history and genetic background.

Neuropeptide Y modulation of ethanol intake: effects of ethanol drinking history and genetic background. Research Abstract Details 

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Neuropeptide Y modulation of ethanol intake: effects of ethanol drinking history and genetic background. Abstract Text:

Nancy E Badia-Elder,Nicholas W Gilpin,Robert B Stewart,

Intracerebroventricular administration of NPY suppresses ethanol intake in selectively bred alcohol-preferring rat lines, but not in rats selectively bred for low ethanol drinking or in unselected Wistar rats, when access to ethanol is limited to 2h/day. However, when rats undergo chronic (24h/day) ethanol drinking (or exposure to ethanol by vapor inhalation) and have periods of imposed ethanol abstinence, the reductions in ethanol drinking following NPY administration are enhanced in alcohol-preferring rats and are also observed in unselected Wistar rats. Thus, sensitivity to the effects of NPY on ethanol drinking appears to be altered by selective breeding for ethanol preference and by a prior history of chronic but intermittent exposure to ethanol.

Neuropeptide Y modulation of ethanol intake: effects of ethanol drinking history and genetic background. Publishing Authors By Initials

NE Badia-Elder,NW Gilpin,RB Stewart,

For similar animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats: rats, wistar research abstracts see: animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats: rats, wistar research

PUBMED ID PMID:

MEDLINE DATE:

Neuropeptide Y modulation of ethanol intake: effects of ethanol drinking history and genetic background. Journal Published:

PUBLICATION TYPE: Review

Journal: Peptides

VOLUME: 28

Page Numbers: 339-44

Journal Abbreviation: Peptides

ISSN: 0196-9781

DAY: 21

MONTH: 12

YEAR: 2006

Neuropeptide Y modulation of ethanol intake: effects of ethanol drinking history and genetic background. Information

Number of References: 57

LANGUAGE: eng

NlmUniqueID: 8008690

Neuropeptide Y modulation of ethanol intake: effects of ethanol drinking history and genetic background. Keywords Mesh Terms:

KEYWORDS: Rats, Wistar

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Neuropeptide Y modulation of ethanol intake: effects of ethanol drinking history and genetic background. Information

Substance Name: Neuropeptide Y

Registry Number: 0

Grant and Affiliation Information for Neuropeptide Y modulation of ethanol intake: effects of ethanol drinking history and genetic background.

AFFILIATION: Department of Psychology, Indiana University Purdue University at Indianapolis (IUPUI), 402 N. Blackford Street, LD 124, Indianapolis, IN 46202, United States. nbadiael@iupui.edu

Country: United States

AGENCY: United States NIAAA

GRANT: AA12857

ACRONYM: AA

MEDLINETA: Peptides

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