[Neuropathological principles of behavioral disorders in dementia]

[Neuropathological principles of behavioral disorders in dementia] Research Abstract Details 

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[Neuropathological principles of behavioral disorders in dementia] Abstract Text:

Psychotic symptoms, apathy, agitation and aggressiveness are behavioral disorders that occur frequently in patients with Alzheimer's dementia. They cause serious problems for patients, relatives and care-givers. These behavioral disorders are associated with neuropathologic changes and alterations of brain metabolism in specific brain areas. Disturbances in mesotemporal and frontal brain areas seem to be related to psychotic symptoms. Apathy is associated with dysfunction of frontal cortical areas. Agitation and impulsivity appear to result from a hypofunction of the serotonin system in association with a relative hyperfunction of dopaminergic and noradrenergic systems. These dysfunctions are the result of direct neuropathologic changes, but also due to cholinergic deficits that seem to both contribute synergistically to and independently cause behavioral disturbances.

[Neuropathological principles of behavioral disorders in dementia] Publishing Authors By Initials

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[Neuropathological principles of behavioral disorders in dementia] Journal Published:

PUBLICATION TYPE: Review

Journal: Praxis

VOLUME: 89

Page Numbers: 1362-5

Journal Abbreviation:

ISSN: 1661-8157

DAY: 31

MONTH: Aug

YEAR: 2000

[Neuropathological principles of behavioral disorders in dementia] Information

Number of References: 10

LANGUAGE: ger

NlmUniqueID: 101468093

[Neuropathological principles of behavioral disorders in dementia] Keywords Mesh Terms:

KEYWORDS: Social Behavior Disorders

MESH TERMS: physiopathology

Chemical & Substance for Abstract: [Neuropathological principles of behavioral disorders in dementia] Information

Substance Name: Neurotransmitter Agents

Registry Number: 0

Grant and Affiliation Information for [Neuropathological principles of behavioral disorders in dementia]

AFFILIATION: Abteilung für Psychiatrische Forschung, Psychiatrische Universitätsklinik Zürich.

Country: SWITZERLAND

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MEDLINETA: Praxis (Bern 1994)

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