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Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood.

Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood. Research Abstract Details 

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  • Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood. Abstract Text:

    l angeliniL Angelini,f zibordiF Zibordi,g zorziG Zorzi,n nardocciN Nardocci,r caporaliR Caporali,a ravelliA Ravelli,a martiniA Martini,l angeliniL Angelini,f zibordiF Zibordi,g zorziG Zorzi,n nardocciN Nardocci,r caporaliR Caporali,a ravelliA Ravelli,a martiniA Martini,

    We report the results of a systematic study on the association of antiphospholipid antibodies (aPLs) with some neurological disease other than stroke in a childhood population. Patients affected by migraine, benign intracranial hypertension (BIH) or unilateral movement disorders, such as hemichorea and hemidystonia with acute-subacute onset, were screened for aPLs. None of them had clinical or serological evidence of Systemic Lupus Erythematosus (SLE) or other connective tissue disease. Moderate to high levels of anticardiolipin antibodies (aCL) and/or positive Lupus Anticoagulant (LA) were demonstrated in 6 out of 17 patients with migraine, in 3 out of 4 patients with BIH and in all of the 5 patients showing unilateral movement disorders. The association between aPLs and these neurological conditions, usually regarded as cryptogenic, may suggest a possible pathogenetic mechanism.

    Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood. Publishing Authors By Initials

    l angeliniL Angelini,f zibordiF Zibordi,g zorziG Zorzi,n nardocciN Nardocci,r caporaliR Caporali,a ravelliA Ravelli,a martiniA Martini,l angeliniL Angelini,f zibordiF Zibordi,g zorziG Zorzi,n nardocciN Nardocci,r caporaliR Caporali,a ravelliA Ravelli,a martiniA Martini,

    For similar nervous system diseases: central nervous system diseases: brain diseases: intracranial hypertension: pseudotumor cerebri research abstracts see: nervous system diseases: central nervous system diseases: brain diseases: intracranial hypertension: pseudotumor cerebri research

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    Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Neuropediatrics

    VOLUME: 27

    Page Numbers: 149-53

    Journal Abbreviation: Neuropediatrics

    ISSN: 0174-304X

    DAY: 16

    MONTH: Jun

    YEAR: 1996

    Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8101187

    Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood. Keywords Mesh Terms:

    KEYWORDS: Pseudotumor Cerebri

    MESH TERMS: immunology

    Chemical & Substance for Abstract: Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood. Information

    Substance Name: Lupus Coagulation Inhibitor

    Registry Number: 0

    Grant and Affiliation Information for Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood.

    AFFILIATION: Department of Neuropediatrics, National Neurological Institute C. Besta, Milano, Italy.

    Country: GERMANY

    GERMANY Research PublicationGERMANY Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Neuropediatrics

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