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Neuroendocrine regulation of food intake.

Neuroendocrine regulation of food intake. Research Abstract Details 

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  • Neuroendocrine regulation of food intake. Abstract Text:

    Maintenance of appropriate stores of metabolic fuels depends on carefully matching caloric intake to caloric expenditure. Achieving such 'energy balance' is a product of complex interactions of peripheral hormones with effector systems in the central nervous system (CNS) that regulate food intake and energy expenditure. Leptin is a hormone that is made in the adipocytes, circulates in the blood and interacts with receptors in the CNS. These receptors can be found in two different types of systems. One effector system is termed 'anabolic' and is activated by low levels of leptin during negative energy balance. This system (exemplified by the hypothalamic neuropeptide Y system) increases food intake and decreases energy expenditure to facilitate the regaining of lost energy stores. The other effector system is termed 'catabolic' and is activated by high levels of leptin during positive energy balance. This system (exemplified by the hypothalamic melanocortin and corticotrophin-releasing hormone systems) decreases food intake and increases energy expenditure to facilitate the loss of excess energy stores. Further understanding of these systems is necessary to develop adequate treatments for disorders of energy balance, such as obesity and wasting.

    Neuroendocrine regulation of food intake. Publishing Authors By Initials

    For similar proteins research abstracts see: proteins research

    PUBMED ID PMID:

    MEDLINE DATE:

    Neuroendocrine regulation of food intake. Journal Published:

    PUBLICATION TYPE: Review

    Journal: Acta paediatrica (Oslo, Norway : 1992). Supplement

    VOLUME: 88

    Page Numbers: 58-61

    Journal Abbreviation: Acta Paediatr Suppl

    ISSN: 0803-5326

    DAY: 12

    MONTH: Feb

    YEAR: 1999

    Neuroendocrine regulation of food intake. Information

    Number of References: 37

    LANGUAGE: eng

    NlmUniqueID: 9315043

    Neuroendocrine regulation of food intake. Keywords Mesh Terms:

    KEYWORDS: Proteins

    MESH TERMS: pharmacology

    Chemical & Substance for Abstract: Neuroendocrine regulation of food intake. Information

    Substance Name: Proteins

    Registry Number: 0

    Grant and Affiliation Information for Neuroendocrine regulation of food intake.

    AFFILIATION: Department of Psychiatry, University of Cincinnati College of Medicine, Ohio, USA.

    Country: NORWAY

    NORWAY Research PublicationNORWAY Research Publication

    AGENCY: United States NIDDK

    GRANT: DK54890

    ACRONYM: DK

    MEDLINETA: Acta Paediatr Suppl

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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