Neuroendocrine effects of flunarizine treatment in postmenopausal women.

Neuroendocrine effects of flunarizine treatment in postmenopausal women. Research Abstract Details 

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Neuroendocrine effects of flunarizine treatment in postmenopausal women. Abstract Text:

F Facchinetti,G Sances,C Bakalakis,M G Morgillo,P Lottici,C Cicoli,A R Genazzani,

Flunarizine (10 mg/day for 60 days) was given to eight postmenopausal women with common migraine. Plasma LH pulsatility fluctuation, peripheral concentrations of prolactin (PRL), cortisol, beta-endorphin (beta-EP), beta-lipotropin (beta-LPH) and Pain Total Index (PTI) were evaluated before and after treatment. PTI was significantly reduced by flunarizine, which did not affect beta-LPH, beta-EP and cortisol plasma levels. On the contrary, both PRL values and amplitude, and length of LH pulses had increased at the end of treatment. Flunarizine reduced head pain in postmenopausal women. However, the enhancement of both PRL and LH release indicates that this calcium antagonist might interfere with the dopaminergic tonus.

Neuroendocrine effects of flunarizine treatment in postmenopausal women. Publishing Authors By Initials

F Facchinetti,G Sances,C Bakalakis,MG Morgillo,P Lottici,C Cicoli,AR Genazzani,

For similar hormones, hormone substitutes, and hormone antagonists: hormones: peptide hormones: hypothalamic hormones: pro-opiomelanocortin: beta-endorphin research abstracts see: hormones, hormone substitutes, and hormone antagonists: hormones: peptide hormones: hypothalamic hormones: pro-opiomelanocortin: beta-endorphin research

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Neuroendocrine effects of flunarizine treatment in postmenopausal women. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Cephalalgia : an international journal of headache

VOLUME: 5 Suppl 2

Page Numbers: 187-8

Journal Abbreviation: Cephalalgia

ISSN: 0333-1024

DAY: 11

MONTH: May

YEAR: 1985

Neuroendocrine effects of flunarizine treatment in postmenopausal women. Information

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LANGUAGE: eng

NlmUniqueID: 8200710

Neuroendocrine effects of flunarizine treatment in postmenopausal women. Keywords Mesh Terms:

KEYWORDS: beta-Endorphin

MESH TERMS: blood

Chemical & Substance for Abstract: Neuroendocrine effects of flunarizine treatment in postmenopausal women. Information

Substance Name: Luteinizing Hormone

Registry Number: 9002-67-9

Grant and Affiliation Information for Neuroendocrine effects of flunarizine treatment in postmenopausal women.

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Country: NORWAY

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MEDLINETA: Cephalalgia

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