New fundamental results on stem cell biology have been obtained in the past 15 years. These results allow us to reinterpret the functioning of the cerebral tissue in health and disease. Proliferating stem cells have been found in the adult brain, which can be involved in postinjury repair and can replace dead cells under specific conditions. Numerous genomic mechanisms controlling stem cell proliferation and differentiation have been identified. The involvement of stem cells in the genesis of malignant tumors has been demonstrated. Neural stem cell tropism toward tumors has been shown. These findings suggest new lines of research on brain functioning and development. Stem cells can be used to develop radically new treatments of neurodegenerative and cancer diseases of the brain.
Neural stem cells in the Mammalian brain. Publishing Authors By Initials
Neural stem cells in the Mammalian brain. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: International review of cytology
VOLUME: 265
Page Numbers: 55-109
Journal Abbreviation: Int. Rev. Cytol.
ISSN: 0074-7696
DAY: 15
MONTH: 02
YEAR: 2008
Neural stem cells in the Mammalian brain. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 2985180
Neural stem cells in the Mammalian brain. Keywords Mesh Terms:
KEYWORDS:
MESH TERMS:
Chemical & Substance for Abstract: Neural stem cells in the Mammalian brain. Information
Substance Name:
Registry Number:
Grant and Affiliation Information for Neural stem cells in the Mammalian brain.
AFFILIATION: Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334 Russia; Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow, 119071 Russia.
Country: United States
AGENCY:
GRANT:
ACRONYM:
MEDLINETA: Int Rev Cytol
REFSOURCE:
DATABASENAME:
ACCESSION NUMBER:
Number Hits: 0
Neural stem cells in the Mammalian brain Related Publications