Shy-Drager Syndrome

"A progressive neurodegenerative condition of the central and autonomic nervous systems characterized by atrophy of the preganglionic lateral horn neurons of the thoracic spinal cord. This disease is generally considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Affected individuals present in the fifth or sixth decade with ORTHOSTASIS and bladder dysfunction; and later develop FECAL INCONTINENCE; anhidrosis; ATAXIA; IMPOTENCE; and alterations of tone suggestive of basal ganglia dysfunction. (From Adams et al.

Abstracts

- Growth hormone response to clonidine is impaired in patients with central sympathetic degeneration. Serum growth hormone (GH) levels before and after intravenous clonidine (1.5 mcg/Kg) were measured in normal subjects and patients with chronic idiopathic...

- [Orthostatic dyskinetic syndrome ("Shy-Drager"). A neurological system degeneration]

- [The shy-drager syndrom, a disease of second half of life (author's transl)] As an example are represented in three processes of disease of Shy-Drager-Syndrom pathogenesis, diagnosis, and therapy. The leading symptom manifested in...