[Nerve growth factor auto-antibodies in the sera of mothers of schizophrenic children and children from high risk group]

[Nerve growth factor auto-antibodies in the sera of mothers of schizophrenic children and children from high risk group] Research Abstract Details 

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[Nerve growth factor auto-antibodies in the sera of mothers of schizophrenic children and children from high risk group] Abstract Text:

O M Zakharenko,T P Kliushnik,I A Kozlova,G V Kozlovskaia,E V Danilovskaia,V M Bashina,V M Simashkova,A V Goriunova,M A Kalinina,

A level of autoantibodies (aAB) to nerve growth factor (NGF) was measured in blood serum of children from 4 groups: 1) schizophrenic patients; 2) children from the families, in which one of the parents suffered with schizophrenia (high risk groups of schizophrenia); 3) children with residual-organic damages of CNS; 4) control group. This index was also determined in their mothers. Significant elevation of a titer of aAB to NGF was observed in blood of children from groups 1 and 2 as well as in their mothers, as compared with 3 and 4 groups. Among the mothers of the children from 1 and 2 groups there were met women with different endogenous mental disorders, with the disorders of personality as well as mentally healthy women. An increase of a level of aAB to NGF was found in all the women from groups 1 and 2, independently of their mental status including mentally healthy women. Such results allow to consider elevated level of aAB to NGF as a risk factor of mental pathology.

[Nerve growth factor auto-antibodies in the sera of mothers of schizophrenic children and children from high risk group] Publishing Authors By Initials

OM Zakharenko,TP Kliushnik,IA Kozlova,GV Kozlovskaia,EV Danilovskaia,VM Bashina,VM Simashkova,AV Goriunova,MA Kalinina,

For similar behavioral disciplines and activities: schizophrenic psychology research abstracts see: behavioral disciplines and activities: schizophrenic psychology research

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[Nerve growth factor auto-antibodies in the sera of mothers of schizophrenic children and children from high risk group] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsak

VOLUME: 99

Page Numbers: 44-6

Journal Abbreviation:

ISSN: 1997-7298

DAY: 31

MONTH: 03

YEAR: 1999

[Nerve growth factor auto-antibodies in the sera of mothers of schizophrenic children and children from high risk group] Information

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LANGUAGE: rus

NlmUniqueID: 9712194

[Nerve growth factor auto-antibodies in the sera of mothers of schizophrenic children and children from high risk group] Keywords Mesh Terms:

KEYWORDS: Schizophrenic Psychology

MESH TERMS: immunology

Chemical & Substance for Abstract: [Nerve growth factor auto-antibodies in the sera of mothers of schizophrenic children and children from high risk group] Information

Substance Name: Nerve Growth Factors

Registry Number: 0

Grant and Affiliation Information for [Nerve growth factor auto-antibodies in the sera of mothers of schizophrenic children and children from high risk group]

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Country: RUSSIA

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MEDLINETA: Zh Nevrol Psikhiatr Im S S Kor

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