Neonatal tolerance and patent filarial infection.

Neonatal tolerance and patent filarial infection. Research Abstract Details 

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Neonatal tolerance and patent filarial infection. Abstract Text:

T V Rajan,

Lymphatic filariasis occurs in endemic pockets. Patent infections with long-term, high-grade microfilaremia do not develop in nonendemic individuals. It is tempting to speculate that individuals with intact immune responses to filarial antigens are capable of dealing with filarial exposure without developing persistent infection. There are published data that support the idea that only those individuals who are impaired in their immune defense against these parasites owing to neonatal tolerization become productively infected with the filarial parasites. If the model is correct, there are profound implications for global eradication.

Neonatal tolerance and patent filarial infection. Publishing Authors By Initials

TV Rajan,

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Neonatal tolerance and patent filarial infection. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Trends in parasitology

VOLUME: 23

Page Numbers: 459-62

Journal Abbreviation: Trends Parasitol.

ISSN: 1471-4922

DAY: 20

MONTH: 09

YEAR: 2007

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LANGUAGE: eng

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Grant and Affiliation Information for Neonatal tolerance and patent filarial infection.

AFFILIATION: Department of Pathology, 263 Farmington Avenue, Farmington, CT 06032, USA. rajan@neuron.uchc.edu

Country: England

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MEDLINETA: Trends Parasitol

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