Neoadjuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy.

Neoadjuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy. Research Abstract Details 

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Neoadjuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy. Abstract Text:

A 71-year-old man with advanced left renal cell carcinoma (lymph node involvement and vena cava thrombus) was submitted to 6 months of neoadjuvant treatment with sorafenib before open radical nephrectomy. After sorafenib treatment and before surgery a new CT scan confirmed the presence of a 9.0 cm in diameter solid mass in the left kidney but a reduction in thrombus extension, limited to the left renal vein. At histological examination after radical nephrectomy, over 90% of the renal mass was substituted by necrotic tissue.

Neoadjuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy. Publishing Authors By Initials

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Neoadjuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Urologia internationalis

VOLUME: 80

Page Numbers: 451-3

Journal Abbreviation: Urol. Int.

ISSN: 1423-0399

DAY: 27

MONTH: 06

YEAR: 2008

Neoadjuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy. Information

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LANGUAGE: eng

NlmUniqueID: 417373

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AFFILIATION: Department of Urology, University of Rome, Rome, Italy.

Country: Switzerland

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MEDLINETA: Urol Int

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