Neoadjuvant chemotherapy: an alternative option of treatment for locally advanced cervical cancer.

Neoadjuvant chemotherapy: an alternative option of treatment for locally advanced cervical cancer. Research Abstract Details 

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Neoadjuvant chemotherapy: an alternative option of treatment for locally advanced cervical cancer. Abstract Text:

V Loizzi,G Cormio,M Vicino,L Selvaggi,

Although the incidence of cervical cancer has declined in both North America and Europe, it still represents the second most common cancer in women and the fifth most common malignancy worldwide. Most patients in the developed countries present with disease either confined to the cervix or with limited extension beyond it. Historically, the standard treatment was usually radiotherapy or radical hysterectomy with node dissection. In 1999, five randomized clinical trials performed by the Gynecologic Oncology Group, the Radiation Therapy Oncology Group and the Southwest Oncology Group have demonstrated a significant outcome advantage when cisplatin-based chemotherapy was administered during radiation in patients with cervical cancer. In the current review, we will analyze the role of neoadjuvant chemotherapy followed by radiotherapy and surgery as an alternative option treatment to the standard chemoradiation for locally advanced cervical cancer (stage Ib2 or larger).

Neoadjuvant chemotherapy: an alternative option of treatment for locally advanced cervical cancer. Publishing Authors By Initials

V Loizzi,G Cormio,M Vicino,L Selvaggi,

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Neoadjuvant chemotherapy: an alternative option of treatment for locally advanced cervical cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Gynecologic and obstetric investigation

VOLUME: 65

Page Numbers: 96-103

Journal Abbreviation: Gynecol. Obstet. Invest.

ISSN: 1423-002X

DAY: 19

MONTH: 09

YEAR: 2007

Neoadjuvant chemotherapy: an alternative option of treatment for locally advanced cervical cancer. Information

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LANGUAGE: eng

NlmUniqueID: 7900587

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Grant and Affiliation Information for Neoadjuvant chemotherapy: an alternative option of treatment for locally advanced cervical cancer.

AFFILIATION: Division of Gynecology Oncology, Department of Obstetrics Gynecology and Neonatology, University of Bari, Bari, Italy.

Country: Switzerland

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MEDLINETA: Gynecol Obstet Invest

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