Neglected infections of poverty in the United States of america.

Neglected infections of poverty in the United States of america. Research Abstract Details 

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Neglected infections of poverty in the United States of america. Abstract Text:

In the United States, there is a largely hidden burden of diseases caused by a group of chronic and debilitating parasitic, bacterial, and congenital infections known as the neglected infections of poverty. Like their neglected tropical disease counterparts in developing countries, the neglected infections of poverty in the US disproportionately affect impoverished and under-represented minority populations. The major neglected infections include the helminth infections, toxocariasis, strongyloidiasis, ascariasis, and cysticercosis; the intestinal protozoan infection trichomoniasis; some zoonotic bacterial infections, including leptospirosis; the vector-borne infections Chagas disease, leishmaniasis, trench fever, and dengue fever; and the congenital infections cytomegalovirus (CMV), toxoplasmosis, and syphilis. These diseases occur predominantly in people of color living in the Mississippi Delta and elsewhere in the American South, in disadvantaged urban areas, and in the US-Mexico borderlands, as well as in certain immigrant populations and disadvantaged white populations living in Appalachia. Preliminary disease burden estimates of the neglected infections of poverty indicate that tens of thousands, or in some cases, hundreds of thousands of poor Americans harbor these chronic infections, which represent some of the greatest health disparities in the United States. Specific policy recommendations include active surveillance (including newborn screening) to ascertain accurate population-based estimates of disease burden; epidemiological studies to determine the extent of autochthonous transmission of Chagas disease and other infections; mass or targeted treatments; vector control; and research and development for new control tools including improved diagnostics and accelerated development of a vaccine to prevent congenital CMV infection and congenital toxoplasmosis.

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Neglected infections of poverty in the United States of america. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: PLoS neglected tropical diseases

VOLUME: 2

Page Numbers: e256

Journal Abbreviation: PLoS Negl Trop Dis

ISSN: 1935-2735

DAY: 25

MONTH: 06

YEAR: 2008

Neglected infections of poverty in the United States of america. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Neglected infections of poverty in the United States of america.

AFFILIATION: Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University and Sabin Vaccine Institute, Washington, D.C., United States of America.

Country: United States

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MEDLINETA: PLoS Negl Trop Dis

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