Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy.

Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy. Research Abstract Details 

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Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy. Abstract Text:

Ravindra K Pandey,Lalit N Goswami,Yihui Chen,Amy Gryshuk,Joseph R Missert,Allan Oseroff,Thomas J Dougherty,

The purpose of this review is to call attention in the use of chlorophyll-a and bacteriochlorophyll-a to develop more than 600 photosensitizers (lambda (max) 660 nm-800 nm) during the last 15 years (1990-2005) at the Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo. This article mainly includes the chemistry, preclinical results, and brief clinical data of some of the most effective photosensitizers. The utility of the tumor-avid photosensitizers in developing multimodality agents (imaging and therapy) is also presented.

Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy. Publishing Authors By Initials

RK Pandey,LN Goswami,Y Chen,A Gryshuk,JR Missert,A Oseroff,TJ Dougherty,

For similar chemical actions and uses: pharmacologic actions: physiological effects of drugs: radiation-sensitizing agents: photosensitizing agents research abstracts see: chemical actions and uses: pharmacologic actions: physiological effects of drugs: radiation-sensitizing agents: photosensitizing agents research

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Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy. Journal Published:

PUBLICATION TYPE: Review

Journal: Lasers in surgery and medicine

VOLUME: 38

Page Numbers: 445-67

Journal Abbreviation:

ISSN: 0196-8092

DAY: 3

MONTH: Jun

YEAR: 2006

Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy. Information

Number of References: 100

LANGUAGE: eng

NlmUniqueID: 8007168

Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy. Keywords Mesh Terms:

KEYWORDS: Photosensitizing Agents

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy. Information

Substance Name: Chlorophyll

Registry Number: 1406-65-1

Grant and Affiliation Information for Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy.

AFFILIATION: Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA. Ravindra.Pandey@roswellpark.org

Country: United States

AGENCY: United States NCI

GRANT: R21 CA114053

ACRONYM: CA

MEDLINETA: Lasers Surg Med

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